Capillary leak syndrome

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Capillary Leak Syndrome

Capillary leak syndrome (pronounced: cap-ill-air-ee leak sin-drome), also known as Clarkson's disease or Systemic Capillary Leak Syndrome (SCLS), is a rare medical condition characterized by the leakage of fluid from the capillaries into surrounding tissues, resulting in severe edema, hypotension, and organ failure.

Etymology

The term "capillary leak syndrome" is derived from the English words "capillary" (a type of small blood vessel), "leak" (meaning to allow liquid to escape), and "syndrome" (a group of symptoms that consistently occur together). The condition is named for its primary symptom, which is the leakage of fluid from the capillaries.

Symptoms

The symptoms of capillary leak syndrome can vary greatly from person to person, but they often include sudden onset of swelling in the arms and legs, low blood pressure, and fatigue. In severe cases, the condition can lead to shock, kidney failure, and other serious complications.

Causes

The exact cause of capillary leak syndrome is unknown, but it is thought to be related to an abnormal immune response. Some researchers believe that the condition may be triggered by an infection or other illness, but more research is needed to confirm this theory.

Diagnosis

Diagnosis of capillary leak syndrome is often difficult due to the rarity of the condition and the variability of its symptoms. However, a combination of medical history, physical examination, and laboratory tests can often lead to a diagnosis. These tests may include blood tests to check for low protein levels and imaging studies to look for signs of fluid leakage.

Treatment

Treatment for capillary leak syndrome is primarily supportive and aims to manage the symptoms and prevent complications. This may include intravenous fluids to maintain blood pressure, medications to reduce swelling, and in severe cases, hospitalization for close monitoring and treatment of complications.

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