Monoclonal gammopathy
Monoclonal gammopathy (pronunciation: /ˌmɒnəˈkləʊn(ə)l ˌɡæməˈpæθi/) is a condition characterized by the presence of an abnormal protein, known as a M protein or paraprotein, in the blood. It is produced by a clone of plasma cells, a type of white blood cell.
Etymology
The term "monoclonal gammopathy" is derived from the Greek words "monos" (meaning single), "klon" (meaning twig), and "gammopathy" (meaning disease of the gamma globulins).
Types
There are several types of monoclonal gammopathy, including:
- Monoclonal gammopathy of undetermined significance (MGUS)
- Multiple myeloma
- Waldenström's macroglobulinemia
- Light chain disease
Symptoms
Monoclonal gammopathy often does not cause symptoms. However, in some cases, it can lead to serious conditions such as kidney disease, nervous system disorders, and blood disorders.
Diagnosis
Monoclonal gammopathy is usually detected through a blood test called serum protein electrophoresis (SPEP). Other tests, such as immunofixation electrophoresis (IFE) and free light chain assay, may also be used.
Treatment
Treatment for monoclonal gammopathy depends on the type and severity of the condition. It may include chemotherapy, stem cell transplantation, or immunotherapy.
See also
External links
- Medical encyclopedia article on Monoclonal gammopathy
- Wikipedia's article - Monoclonal gammopathy
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