Barbiturate overdose

Barbiturate Overdose

Barbiturate overdose (/bɑːrˈbɪtʃʊrɪt/), also known as barbiturate poisoning, is a condition that occurs when an individual ingests a dose of barbiturates that exceeds the body's ability to metabolize and excrete them. The term "barbiturate" (/bɑːrˈbɪtʃʊrɪt/) is derived from the name of the chemical compound barbituric acid, which was first synthesized in 1864 by the German chemist Adolf von Baeyer.

Symptoms

Symptoms of a barbiturate overdose can vary widely depending on the specific type and dose of barbiturate taken, as well as the individual's overall health and tolerance to the drug. Common symptoms may include respiratory depression, hypotension, hypothermia, coma, and in severe cases, death.

Causes

Barbiturate overdose can occur as a result of either accidental or intentional ingestion of excessive amounts of barbiturates. This can include both prescription medications such as phenobarbital and secobarbital, as well as illicitly manufactured barbiturates.

Treatment

Treatment for a barbiturate overdose typically involves supportive care, including airway management, intravenous fluids, and monitoring of vital signs. In some cases, activated charcoal may be administered to help absorb the drug in the stomach and prevent further absorption into the body. In severe cases, hemodialysis may be required to remove the drug from the bloodstream.

Prevention

Prevention of barbiturate overdose primarily involves proper prescription practices, patient education, and monitoring of individuals who are at risk of overdose. This includes individuals with a history of substance abuse, those with access to large quantities of barbiturates, and those with a history of suicidal ideation or attempts.

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Barbiturate overdose