Zieve's syndrome

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Zieve's syndrome
Synonyms Zieve syndrome
Pronounce N/A
Specialty N/A
Symptoms Jaundice, hemolytic anemia, hyperlipidemia, abdominal pain
Complications Liver disease, pancreatitis
Onset Acute
Duration Variable
Types N/A
Causes Alcohol use disorder
Risks Chronic alcoholism, liver disease
Diagnosis Clinical diagnosis, blood tests
Differential diagnosis Acute hepatitis, pancreatitis, gallstones
Prevention N/A
Treatment Abstinence from alcohol, supportive care
Medication N/A
Prognosis Generally good with cessation of alcohol use
Frequency Rare
Deaths N/A


Zieve syndrome is a rare syndrome that happens in people who abuse alcohol.

Triad

It has a triad of symptoms: hemolytic anemia, cholestatic jaundice, and transient hyperlipidemia

Diagnosis

Clinical history of ETOh abuse, and the triad of symptoms in a setting of elevated bilirubin, no GI bleeding.

Treatment

Alcohol cessation.

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Contributors: Prab R. Tumpati, MD