7-APBT
Chemical compound
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7-APBT (7-(2-aminopropyl)benzofuran) is a chemical compound that belongs to the class of substituted amphetamines. It is structurally related to other compounds such as MDMA and 6-APB, and is known for its psychoactive properties.
Chemical Structure and Properties
7-APBT is a benzofuran derivative, characterized by the presence of a benzofuran ring system with an attached amphetamine side chain. The chemical formula for 7-APBT is C11H13NO, and it has a molecular weight of 175.23 g/mol.
The compound is typically synthesized in a laboratory setting and is not found naturally. Its structure is similar to that of other psychoactive substances, which contributes to its effects on the central nervous system.
Pharmacology
7-APBT acts primarily as a serotonin and dopamine releasing agent. This means it increases the levels of these neurotransmitters in the brain, leading to its psychoactive effects. The compound is known to produce effects similar to those of MDMA, including euphoria, increased sociability, and enhanced sensory perception.
The exact mechanism of action involves the inhibition of the reuptake of serotonin and dopamine, as well as the promotion of their release from presynaptic neurons. This results in increased concentrations of these neurotransmitters in the synaptic cleft, enhancing their activity.
Effects and Usage
The effects of 7-APBT are dose-dependent and can vary significantly between individuals. Common effects include:
- Euphoria
- Increased energy and alertness
- Enhanced empathy and sociability
- Altered sensory perception
Due to its psychoactive properties, 7-APBT is sometimes used recreationally. However, its use is associated with potential risks, including neurotoxicity, cardiovascular effects, and the potential for addiction.
Legal Status
The legal status of 7-APBT varies by country. In some jurisdictions, it is classified as a controlled substance, making its production, distribution, and possession illegal without proper authorization. In other regions, it may be unregulated, though this is subject to change as new legislation is enacted.
Safety and Toxicity
The safety profile of 7-APBT is not well-established, and its use carries potential risks. Users may experience adverse effects such as increased heart rate, hypertension, anxiety, and insomnia. Long-term use may lead to more serious health issues, including potential damage to the serotonergic system.
Related Compounds
7-APBT is related to several other compounds in the benzofuran and amphetamine families, including:
These compounds share similar structures and pharmacological effects, though they may differ in potency and duration of action.
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Contributors: Prab R. Tumpati, MD