2C2-NBOMe

Chemical compound

2C2-NBOMe
INN
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CAS Number	1539264-32-3
PubChem	71301340
DrugBank
ChemSpider	29761956
KEGG

2C2-NBOMe is a synthetic psychedelic compound belonging to the NBOMe class. It is a derivative of the phenethylamine 2C2, modified with a 2-methoxybenzyl group. This compound is known for its potent hallucinogenic effects and is used primarily in research settings.

Chemical Structure and Properties

Structure of 2C2-NBOMe

2C2-NBOMe is chemically classified as a phenethylamine, with the molecular formula C₁₈H₂₂ClNO₃. The compound features a 2,5-dimethoxyphenethylamine core, similar to other compounds in the 2C family, with a 4-chloro substitution. The addition of the 2-methoxybenzyl group at the nitrogen atom significantly increases its affinity for the serotonin receptors, particularly the 5-HT_2A receptor, which is responsible for its psychedelic effects.

Pharmacology

2C2-NBOMe acts primarily as a potent agonist at the 5-HT_2A receptor, which is a common target for many psychedelic substances. This interaction is believed to be the primary mechanism through which it exerts its hallucinogenic effects. The compound's high potency means that it is active at very low doses, which can increase the risk of overdose and adverse effects.

Effects

The effects of 2C2-NBOMe are similar to those of other NBOMe compounds and include intense visual and auditory hallucinations, altered perception of time, and changes in mood and thought processes. Users may experience euphoria, introspection, and a sense of connection with their surroundings. However, the compound can also cause anxiety, confusion, and paranoia, especially at higher doses.

Safety and Toxicity

Due to its high potency and the variability in individual response, 2C2-NBOMe poses significant risks. Overdose can lead to severe physiological and psychological effects, including tachycardia, hypertension, seizures, and psychosis. The safety profile of 2C2-NBOMe is not well-established, and it is not approved for human consumption.

Legal Status

The legal status of 2C2-NBOMe varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of medical use. Researchers must obtain special licenses to study the compound.

Related Compounds

• 2C-B
• 2C-I
• 25I-NBOMe
• 25C-NBOMe

Related Pages

• Psychedelic drug
• Serotonin receptor
• Hallucinogen