25I-NB4OMe

A synthetic psychedelic drug

25I-NB4OMe
INN
Drug class
Routes of administration	Oral, sublingual, nasal
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status	Uncontrolled
CAS Number	919797-20-9
PubChem	44719443
DrugBank
ChemSpider	23249980
KEGG

25I-NB4OMe is a synthetic psychedelic compound that belongs to the NBOMe class of drugs. It is a derivative of the phenethylamine 2C-I and is known for its potent hallucinogenic effects.

Chemical structure and properties

25I-NB4OMe is chemically classified as a phenethylamine and a substituted amphetamine. Its structure includes a 2,5-dimethoxyphenyl ring with an iodine atom at the 4-position, and a 2-methoxybenzyl group attached to the nitrogen atom of the ethylamine chain. This structure is similar to other compounds in the NBOMe series, such as 25I-NBOMe and 25C-NBOMe.

Pharmacology

25I-NB4OMe acts primarily as a potent agonist of the 5-HT2A receptor, which is the primary target for classical psychedelics like LSD and psilocybin. The activation of this receptor is responsible for the drug's hallucinogenic effects. The compound is known for its high potency, meaning that very small doses can produce significant effects.

Effects

The effects of 25I-NB4OMe are similar to those of other psychedelics, including altered perception of time and space, visual hallucinations, and changes in thought processes. Users may experience enhanced sensory perception, emotional changes, and a sense of euphoria. However, the drug can also cause adverse effects such as anxiety, paranoia, and confusion.

Legal status

The legal status of 25I-NB4OMe varies by country. In some jurisdictions, it is classified as a controlled substance, while in others it remains legal or unregulated. Due to its potent effects and potential for harm, many countries have moved to restrict its sale and distribution.

Safety and risks

The use of 25I-NB4OMe carries significant risks, particularly due to its high potency and the potential for overdose. Adverse effects can include tachycardia, hypertension, hyperthermia, and seizures. There have been reports of fatalities associated with its use, often due to misidentification or improper dosing.

Related pages

• NBOMe series
• 2C-I
• Psychedelic drug
• 5-HT2A receptor

Gallery

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  Chemical structure of 25I-NB4OMe