Tuberculous pericarditis
| Tuberculous pericarditis | |
|---|---|
| Synonyms | TB pericarditis |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Chest pain, fever, dyspnea, cough, night sweats, weight loss |
| Complications | Constrictive pericarditis, cardiac tamponade |
| Onset | Gradual |
| Duration | Weeks to months |
| Types | N/A |
| Causes | Mycobacterium tuberculosis infection |
| Risks | HIV/AIDS, immunosuppression, close contact with TB patients |
| Diagnosis | Chest X-ray, Echocardiography, Pericardial fluid analysis, Tuberculin skin test, Interferon gamma release assay |
| Differential diagnosis | Viral pericarditis, Bacterial pericarditis, Malignant pericarditis |
| Prevention | N/A |
| Treatment | Antitubercular therapy, corticosteroids, pericardiocentesis |
| Medication | Isoniazid, Rifampicin, Pyrazinamide, Ethambutol |
| Prognosis | Variable, depends on early diagnosis and treatment |
| Frequency | More common in regions with high tuberculosis prevalence |
| Deaths | N/A |
Tuberculous pericarditis is a form of pericarditis which is caused by Mycobacterium tuberculosis, the bacterium that causes tuberculosis. This condition is a rare complication of tuberculosis, but it can be life-threatening if not treated promptly.
Symptoms
The symptoms of tuberculous pericarditis can vary, but they often include:
- Chest pain
- Fever
- Night sweats
- Weight loss
- Shortness of breath
- Swelling of the legs or abdomen
Causes
Tuberculous pericarditis is caused by the spread of Mycobacterium tuberculosis from a primary infection elsewhere in the body, often the lungs. This can occur through the bloodstream or through direct extension from the lungs.
Diagnosis
The diagnosis of tuberculous pericarditis can be challenging, as the symptoms can be similar to those of other conditions. The diagnosis is usually confirmed by testing a sample of pericardial fluid or tissue for the presence of Mycobacterium tuberculosis.
Treatment
The treatment for tuberculous pericarditis typically involves a combination of antibiotics to treat the tuberculosis infection and corticosteroids to reduce inflammation. In some cases, surgery may be needed to drain excess fluid from the pericardium.
Prognosis
With prompt and appropriate treatment, most people with tuberculous pericarditis can make a full recovery. However, if left untreated, the condition can lead to serious complications such as cardiac tamponade or constrictive pericarditis.
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Contributors: Prab R. Tumpati, MD