Supramammillary nucleus

From WikiMD's medical encyclopedia


General Information
Latin nucleus supramammillaris
Greek
TA98
TA2
FMA
Details
System Limbic system
Artery Posterior cerebral artery
Vein Cerebral veins
Nerve
Lymphatic drainage
Precursor
Function
Identifiers
Clinical significance
Notes

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The supramammillary nucleus is a small region located in the hypothalamus of the brain. It is situated above the mammillary bodies and plays a crucial role in various neurophysiological processes.

Structure

The supramammillary nucleus is part of the limbic system, which is involved in emotion, behavior, and memory. It is located dorsally to the mammillary bodies and is connected to several other brain regions, including the hippocampus and the thalamus.

Function

The supramammillary nucleus is involved in the regulation of arousal, sleep-wake cycle, and motivation. It has been shown to influence theta rhythm in the hippocampus, which is important for learning and memory processes.

Connections

The supramammillary nucleus has extensive connections with other parts of the brain. It projects to the hippocampus, septal area, and ventral tegmental area. These connections suggest its involvement in reward and motivational pathways.

Clinical significance

Dysfunction of the supramammillary nucleus may be associated with sleep disorders, mood disorders, and cognitive impairments. Research is ongoing to better understand its role in these conditions.

Research

Studies have shown that the supramammillary nucleus is involved in the modulation of dopaminergic activity, which is crucial for reward processing and addiction. Further research is needed to explore its potential as a target for therapeutic interventions.

See also

References


External links

  • [Link to relevant external resource]



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Contributors: Prab R. Tumpati, MD