Poorly differentiated thyroid cancer
| Poorly differentiated thyroid carcinoma
| |
|---|---|
| Synonyms | PDTC
|
Poorly differentiated thyroid carcinoma is malignant neoplasm of follicular cell origin showing intermediate histopathological patterns between differentiated and undifferentiated thyroid cancers.[1]
Histopathology[edit]
- Presence of small cells with round nuclei and scant cytoplasm with a diffuse solid pattern
- Round or oval nests (insulae) or in trabeculae.
- Solid growth and presence of microfollicles, some of which contain dense colloid.
- Extrathyroidal extension and blood vessel invasion
- Foci of necrosis,
- Larger than 5 cm in greatest diameter at diagnosis
Epidemiology[edit]
- PDTC affects predominantly females about 55 years of age
References[edit]
- ↑ "Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach.".Am J Surg Pathol.2007;31(8)
- 1256–64.doi:10.1097/PAS.0b013e3180309e6a.PMID:17667551.
External links[edit]
| Tumours of endocrine glands | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
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