Piperacillin sodium

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Piperacillin Sodium

Piperacillin Sodium (pronounced as pi-per-a-sil-in so-dee-um) is a broad-spectrum Beta-lactam antibiotic used in the treatment of a wide range of bacterial infections. It is a member of the Ureidopenicillin sub-group of Penicillin.

Etymology

The term "Piperacillin" is derived from the Latin word "Piper", meaning pepper, and "acillin", a common suffix used in the naming of penicillin derivatives. The "Sodium" in Piperacillin Sodium refers to the sodium salt form of the drug, which is used to improve its solubility.

Usage

Piperacillin Sodium is used to treat a variety of infections caused by susceptible bacteria, including Pneumonia, Septicemia, Urinary tract infections, and Intra-abdominal infections. It is often used in combination with the beta-lactamase inhibitor Tazobactam to broaden its spectrum of activity.

Mechanism of Action

Piperacillin Sodium works by inhibiting the synthesis of the bacterial cell wall, leading to cell death. It has a high affinity for Penicillin-binding proteins, which are essential for cell wall synthesis in bacteria.

Side Effects

Common side effects of Piperacillin Sodium include Diarrhea, Nausea, Vomiting, and Rash. Serious side effects may include Allergic reactions, Seizures, and Clostridium difficile-associated diarrhea.

Related Terms

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