Noxiptiline
Noxiptiline
Noxiptiline (pronounced nox-ip-tiline), also known as Agedal, Elronon, Nogedal, and Tolpadol, is a tricyclic antidepressant (TCA) that was introduced in Europe in the 1970s for the treatment of depression.
Pronunciation
Noxiptiline is pronounced as "nox-ip-tiline".
Etymology
The term "Noxiptiline" is derived from the chemical structure of the drug, which is a tricyclic compound. The prefix "Noxi-" is derived from the Latin "noxius", meaning harmful or injurious, and "-ptiline" is a common suffix used in the names of tricyclic antidepressants.
Usage
Noxiptiline is used primarily in the treatment of major depressive disorder (MDD), but it may also be used off-label for the treatment of anxiety disorders, insomnia, and chronic pain conditions.
Mechanism of Action
Noxiptiline works by inhibiting the reuptake of serotonin and norepinephrine, two neurotransmitters in the brain that are involved in mood regulation. This increases the levels of these neurotransmitters in the brain, which can help to alleviate the symptoms of depression.
Side Effects
Common side effects of Noxiptiline include dry mouth, constipation, blurred vision, and drowsiness. More serious side effects can include cardiac arrhythmias, orthostatic hypotension, and suicidal ideation.
Related Terms
- Tricyclic antidepressant
- Serotonin
- Norepinephrine
- Major depressive disorder
- Anxiety disorders
- Insomnia
- Cardiac arrhythmias
- Orthostatic hypotension
- Suicidal ideation
External links
- Medical encyclopedia article on Noxiptiline
- Wikipedia's article - Noxiptiline
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