Kidney tumour

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Obesity, Sleep & Internal medicine
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Kidney tumour
File:Renal oncocytoma2.jpg Renal oncocytoma, a type of kidney tumour
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Hematuria, flank pain, abdominal mass
Complications	Metastasis, renal failure
Onset	Varies
Duration	Varies
Types	Renal cell carcinoma, Wilms' tumor, Oncocytoma, Angiomyolipoma
Causes	Genetic mutations, smoking, obesity, hypertension
Risks	Family history, Von Hippel-Lindau disease, Tuberous sclerosis
Diagnosis	Imaging studies, biopsy
Differential diagnosis	Benign kidney cyst, pyelonephritis
Prevention	Smoking cessation, healthy diet, regular exercise
Treatment	Surgery, radiation therapy, chemotherapy, targeted therapy
Medication	Sunitinib, Pazopanib, Everolimus
Prognosis	Depends on stage and type
Frequency	Common
Deaths	N/A

File:Cortical solid mass of renal cell carcinoma.jpg

Cortical solid mass of renal cell carcinoma

File:Renal cell carcinoma with both cystic and solid components.jpg

Renal cell carcinoma with both cystic and solid components

File:Renal tumors by relative incidence and prognosis.png

Renal tumors by relative incidence and prognosis

Kidney tumor refers to an abnormal growth of cells within the kidney, one of the vital organs responsible for filtering waste from the blood and producing urine. Kidney tumors can be benign (non-cancerous) or malignant (cancerous), with the latter having the potential to spread (metastasize) to other parts of the body. The most common type of kidney cancer in adults is Renal cell carcinoma (RCC), while children are more likely to develop a type of cancer called Wilms' tumor.

Causes and Risk Factors

The exact cause of kidney tumors is not fully understood, but several risk factors have been identified. These include smoking, obesity, high blood pressure, genetic mutations, and long-term dialysis. Exposure to certain chemicals, such as those used in the manufacturing of leather goods, can also increase the risk.

Symptoms

In the early stages, kidney tumors may not cause any symptoms. As the tumor grows, symptoms may include blood in the urine (hematuria), persistent pain in the side or back, a mass or lump in the side or abdomen, fatigue, unexplained weight loss, and fever.

Diagnosis

Diagnosis of a kidney tumor typically involves a combination of physical exams, blood and urine tests, imaging tests (such as ultrasound, CT scans, and MRI), and a biopsy. The biopsy, where a small sample of tissue is removed and examined under a microscope, is crucial for determining whether the tumor is benign or malignant.

Treatment

Treatment options for kidney tumors depend on the type, size, and stage of the tumor, as well as the patient's overall health. Options may include surgery (to remove part or all of the kidney), targeted therapy, immunotherapy, radiation therapy, and chemotherapy. In cases where the tumor is small and not causing any symptoms, active surveillance may be recommended to monitor the tumor for any changes.

Prognosis

The prognosis for kidney tumors varies widely depending on the type and stage of the tumor at diagnosis. Early detection and treatment of kidney tumors can significantly improve the prognosis. Renal cell carcinoma, if detected early, often has a favorable prognosis, while advanced or metastatic RCC can be challenging to treat. Wilms' tumor, with current treatment protocols, has a high cure rate in children.

Prevention

While there is no guaranteed way to prevent kidney tumors, reducing the risk factors can help. This includes quitting smoking, maintaining a healthy weight, controlling blood pressure, and avoiding exposure to harmful chemicals.