Gadoxetate disodium
Gadoxetate Disodium
Gadoxetate Disodium (pronunciation: ga-DOX-e-tate dye-SOE-dee-um) is a contrast agent used in magnetic resonance imaging (MRI) to help create clear images of the liver. It is known commercially as Eovist in the United States and Primovist in Europe.
Etymology
The term "Gadoxetate Disodium" is derived from the chemical composition of the compound. "Gad" refers to Gadolinium, a rare earth metal used in MRI contrast agents. "Oxetate" is derived from oxetic acid, which is used to chelate the gadolinium, and "disodium" refers to the two sodium atoms present in the compound.
Usage
Gadoxetate Disodium is administered intravenously to patients undergoing liver MRI. It helps to enhance the contrast in the images, making it easier to identify and characterize lesions in the liver. It is particularly useful in detecting hepatocellular carcinoma, a common type of liver cancer.
Related Terms
- Contrast Agent: A substance used to enhance the contrast of structures or fluids within the body in medical imaging.
- Magnetic Resonance Imaging: A type of imaging technique that uses a magnetic field and radio waves to create detailed images of the organs and tissues within the body.
- Gadolinium: A chemical element with the symbol Gd and atomic number 64. Gadolinium is used in MRI contrast agents due to its paramagnetic properties.
- Hepatocellular Carcinoma: A primary malignancy of the liver and occurs predominantly in patients with underlying chronic liver disease and cirrhosis.
Side Effects
Like all medications, Gadoxetate Disodium can cause side effects. Common side effects include nausea, headache, and dizziness. In rare cases, it can cause a serious allergic reaction. Patients with kidney problems should use this medication with caution, as gadolinium-based contrast agents can increase the risk of a rare but serious condition called nephrogenic systemic fibrosis.
External links
- Medical encyclopedia article on Gadoxetate disodium
- Wikipedia's article - Gadoxetate disodium
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