Metrizoic acid
Metrizoic acid is an organoiodine compound that has seen application as a contrast medium in radiological imaging. Its use in the medical field has been substantial, though it's important to recognize the inherent risks associated with its administration due to its high osmolality.
Chemical and Physical Properties
Metrizoic acid is classified under the umbrella of ionic, high osmolality contrast agents. These agents inherently contain a high number of particles in solution, leading to its high osmolality. This characteristic is a critical determinant in its biological behavior and associated risks[1].
Clinical Applications
Metrizoic acid has been utilized in a variety of diagnostic imaging processes including:
- Computed tomography (CT) scans
- Intravenous urography
- Angiography
- As a contrast agent, it serves to enhance the differentiation between tissues, thereby improving the clarity and quality of imaging[2].
Risks and Adverse Effects
- While Metrizoic acid has been a valuable tool in radiological imaging, it's not without its concerns. The high osmolality of Metrizoic acid makes it more hypertonic compared to the plasma. This difference in osmolality is linked with a higher risk of inducing allergic reactions, especially when compared to lower osmolar or non-ionic contrast media[3]. Reactions can range from mild (e.g., rash, itching) to severe, including anaphylaxis.
- Healthcare providers should be equipped with the necessary tools and medications to address such reactions, ensuring patient safety. Moreover, thorough patient history, especially regarding allergies and prior contrast media reactions, can help in identifying those at elevated risk.
Conclusion
Metrizoic acid, with its distinctive chemical properties and osmolality, has played a crucial role in radiological imaging. It is, however, paramount for medical professionals to understand its associated risks and to be vigilant during its administration to ensure both effective imaging and patient safety.
| Contrast media (V08) | ||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
References
- Strickland, N. H. (1991). Ionic and non-ionic iodinated contrast media: a perspective. Radiography, 57(1), 13-17.
- Dawson, P., & Clauss, W. (1999). Ionic and nonionic contrast media – mechanisms and consequences. European Journal of Radiology, 29, S44-S47.
- Barrett, B. J., & Carlisle, E. J. (1993). Metaanalysis of the relative nephrotoxicity of high- and low-osmolality iodinated contrast media. Radiology, 188(1), 171-178.
- ↑ Strickland, N. H. (1991). Ionic and non-ionic iodinated contrast media: a perspective. Radiography, 57(1), 13-17.
- ↑ Dawson, P., & Clauss, W. (1999). Ionic and nonionic contrast media – mechanisms and consequences. European Journal of Radiology, 29, S44-S47.
- ↑ Barrett, B. J., & Carlisle, E. J. (1993). Metaanalysis of the relative nephrotoxicity of high- and low-osmolality iodinated contrast media. Radiology, 188(1), 171-178.
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Contributors: Prab R. Tumpati, MD
