Fertile eunuch syndrome

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Fertile Eunuch Syndrome

Fertile eunuch syndrome (pronunciation: /ˈfɜːr.taɪl/ /ˈjuː.nək/ /ˈsɪn.droʊm/), also known as Hypogonadotropic hypogonadism (pronunciation: /ˌhaɪ.poʊ.ɡəˈnæd.əˌtroʊ.pɪk/ /ˌhaɪ.poʊ.ɡəˈnæd.ɪ.zəm/), is a rare condition characterized by delayed or absent puberty and infertility in males. The term "fertile eunuch" is a misnomer as affected individuals are typically infertile.

Etymology

The term "fertile eunuch syndrome" is derived from the Greek words "eunoukhos" (meaning "bed guard") and "syndrome" (meaning "running together"). The term "hypogonadotropic hypogonadism" is derived from the Greek words "hypo" (meaning "under"), "gonad" (meaning "sex gland"), and "tropos" (meaning "a turning").

Symptoms

The primary symptoms of fertile eunuch syndrome include delayed or absent puberty, small testes, and low levels of testosterone. Additional symptoms may include decreased muscle mass, reduced body hair, and gynecomastia.

Causes

Fertile eunuch syndrome is caused by a deficiency in the production of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This results in decreased production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by the pituitary gland, leading to underdevelopment of the testes and low testosterone levels.

Diagnosis

Diagnosis of fertile eunuch syndrome is based on clinical symptoms, hormone testing, and genetic testing. Hormone tests typically show low levels of LH, FSH, and testosterone. Genetic testing may be used to identify mutations in genes associated with the condition.

Treatment

Treatment for fertile eunuch syndrome typically involves hormone replacement therapy to increase testosterone levels. This can help to induce puberty and improve sexual function. In some cases, fertility may be achieved through assisted reproductive techniques.

Related Terms

External links

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