Drug-induced lupus
Drug-induced lupus
Drug-induced lupus (pronunciation: /drʌg ɪnˈdjuːst ˈluːpəs/) is a lupus-like syndrome that is triggered by certain prescription drugs. It is similar to systemic lupus erythematosus (SLE), a chronic inflammatory disease that can affect any part of the body, but drug-induced lupus typically causes fewer problems.
Etymology
The term "lupus" is derived from the Latin word for wolf, due to the characteristic rash that was thought to resemble a wolf's bite. The term "drug-induced" refers to the fact that the condition is triggered by medication.
Symptoms
Symptoms of drug-induced lupus can vary, but often include arthralgia (joint pain), myalgia (muscle pain), serositis (inflammation of the lining of the lungs or heart), and fatigue. A characteristic rash may also appear on the face, resembling a butterfly.
Causes
Drug-induced lupus is caused by a reaction to certain medications. These can include hydralazine, used to treat high blood pressure, and procainamide, used to treat irregular heart rhythms. Other drugs that can cause this condition include isoniazid, quinidine, and minocycline.
Diagnosis
Diagnosis of drug-induced lupus is based on a combination of symptoms, medical history, and laboratory tests. The presence of certain autoantibodies in the blood, such as anti-histone antibodies, can help confirm the diagnosis.
Treatment
Treatment for drug-induced lupus involves discontinuing the medication that caused the condition. Symptoms usually resolve within weeks to months after the drug is stopped. In some cases, corticosteroids or nonsteroidal anti-inflammatory drugs (NSAIDs) may be used to manage symptoms.
See also
External links
- Medical encyclopedia article on Drug-induced lupus
- Wikipedia's article - Drug-induced lupus
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