Casirivimab/imdevimab

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Casirivimab/Imdevimab

Casirivimab/Imdevimab (pronunciation: kuh-sir-uh-vim-ab/im-dev-im-ab) is a combination of two monoclonal antibodies used for the treatment of mild to moderate coronavirus disease 2019 (COVID-19) in certain patients.

Etymology

The names "Casirivimab" and "Imdevimab" are derived from the International Nonproprietary Names (INN) system, which is used to name pharmaceutical substances. The "-vimab" suffix is used for monoclonal antibodies.

Usage

Casirivimab and imdevimab are administered together for the treatment of COVID-19 in individuals who are at high risk for progressing to severe COVID-19 and/or hospitalization. This includes those who are 65 years of age or older, or who have certain chronic medical conditions.

Mechanism of Action

Casirivimab and imdevimab are monoclonal antibodies that are specifically directed against the spike protein of SARS-CoV-2, designed to block the virus’ attachment and entry into human cells.

Related Terms

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