Angiomatoid fibrous histiocytoma

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Angiomatoid fibrous histiocytoma (pronunciation: an-gee-oh-ma-toyd fy-brous his-tee-oh-sy-toh-ma) is a rare type of soft tissue sarcoma that typically occurs in children and young adults.

Etymology

The term "angiomatoid" is derived from the Greek words angeion (vessel), -oma (tumor), and -oid (like), indicating that the tumor resembles a vascular structure. "Fibrous" refers to the fibrous tissue that makes up part of the tumor, and "histiocytoma" is derived from the Greek words histio (tissue) and -cytoma (tumor), indicating that the tumor originates from histiocytes, a type of immune cell.

Description

Angiomatoid fibrous histiocytoma is characterized by the presence of blood-filled spaces surrounded by fibrous tissue and histiocytes. The tumor is usually located in the deep dermis or subcutaneous tissue, most commonly in the extremities, but can also occur in other parts of the body such as the head, neck, and trunk.

Symptoms

Symptoms of angiomatoid fibrous histiocytoma may include a painless lump or swelling, skin discoloration, and limited range of motion if the tumor is located near a joint.

Diagnosis

Diagnosis of angiomatoid fibrous histiocytoma is typically made through a combination of medical imaging studies and biopsy. The tumor has a distinctive appearance on histopathological examination, with a pseudocapsule of lymphoid tissue surrounding the tumor and areas of hemorrhage and necrosis within the tumor.

Treatment

Treatment for angiomatoid fibrous histiocytoma typically involves surgical removal of the tumor. In some cases, radiation therapy or chemotherapy may be used in addition to surgery.

Prognosis

The prognosis for individuals with angiomatoid fibrous histiocytoma is generally good, with a high rate of long-term survival. However, the tumor can recur, and in rare cases, it can metastasize to other parts of the body.

See also

External links

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