Amplified musculoskeletal pain syndrome

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Amplified musculoskeletal pain syndrome
Hyperalgesia and allodynia.tif
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Chronic pain, allodynia, hyperalgesia, muscle weakness, fatigue
Complications N/A
Onset Typically in childhood or adolescence
Duration Variable, can be chronic
Types N/A
Causes Unknown, possibly related to psychological stress, injury, or infection
Risks Female gender, family history of pain disorders, psychological stress
Diagnosis Clinical diagnosis based on symptoms and exclusion of other conditions
Differential diagnosis Fibromyalgia, complex regional pain syndrome, juvenile idiopathic arthritis
Prevention N/A
Treatment Physical therapy, cognitive behavioral therapy, medication for pain management
Medication N/A
Prognosis Variable; some patients improve with treatment, others may have persistent symptoms
Frequency Unknown, but considered rare
Deaths N/A


Amplified Musculoskeletal Pain Syndrome (AMPS) is a condition characterized by an abnormal pain response in the muscles, bones, and joints. This syndrome is often seen in children and adolescents, although it can occur in adults as well. The pain experienced in AMPS is typically more intense than what would be expected from the initial injury or condition.

Symptoms

The primary symptom of AMPS is chronic pain that is disproportionate to the initial cause. Other symptoms may include:

Causes

The exact cause of AMPS is not well understood. However, it is believed to involve a combination of physical and psychological factors. Potential triggers include:

  • Physical injury or trauma
  • Infection
  • Psychological stress
  • Genetic predisposition

Diagnosis

Diagnosis of AMPS is primarily clinical, based on the patient's history and symptoms. Diagnostic criteria may include:

  • Persistent pain that is disproportionate to the initial injury
  • Absence of other medical conditions that could explain the pain
  • Physical examination findings such as hyperalgesia and allodynia

Treatment

Treatment for AMPS typically involves a multidisciplinary approach, including:

Prognosis

With appropriate treatment, many individuals with AMPS can achieve significant improvement in their symptoms. Early intervention is crucial for the best outcomes.

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Contributors: Prab R. Tumpati, MD