Advanced maternal age

Women over age 34 (age 35 at delivery) at increased risk fornondisjunction trisomy in fetus.

Advanced Maternal Age

Advanced maternal age

Advanced maternal age, often referred to as AMA, is a term traditionally used by medical professionals to describe women who are pregnant or attempting to become pregnant at age 35 or older. Advanced maternal age can have implications for both the mother and the fetus during pregnancy.

Overview

The age at which women are having their first child has been increasing in many parts of the world. Several factors contribute to this trend, including societal changes, personal and professional choices, and advancements in fertility treatments.

Risks Associated with AMA

Pregnancies in women of advanced maternal age are associated with an increased risk of:

• Chromosomal abnormalities, including Down syndrome
• Miscarriage
• Gestational diabetes
• Preeclampsia
• Cesarean section

Fertility and AMA

Women's fertility generally decreases with age. This decline becomes more pronounced as women enter their 30s, particularly after age 35. Women of advanced maternal age may experience:

• Decreased ovulation frequency
• Reduced quality of eggs
• Reduced ovarian reserve

Prenatal Testing and Monitoring

Due to the increased risks associated with AMA, additional prenatal testing and monitoring may be recommended, including:

• Amniocentesis
• Chorionic villus sampling (CVS)
• Detailed ultrasounds

See Also

• Pregnancy risks by age
• Prenatal care

References

• "Advanced Maternal Age and Pregnancy Risks" - American College of Obstetricians and Gynecologists.
• "Age and Fertility: A Guide for Patients" - American Society for Reproductive Medicine.