6-APBT
Chemical compound
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| CAS Number | 286834-85-3 |
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6-APBT (6-(2-aminopropyl)benzothiophene) is a chemical compound that belongs to the class of substituted amphetamines. It is structurally related to other compounds such as 6-APB and 6-APDB, which are known for their psychoactive properties. 6-APBT is primarily of interest in the field of research chemicals and has been studied for its potential effects on the central nervous system.
Chemical Structure and Properties
6-APBT is a derivative of benzothiophene, a bicyclic compound consisting of a benzene ring fused to a thiophene ring. The compound features an amino group attached to the propyl side chain at the sixth position of the benzothiophene ring. This structural configuration is similar to that of other phenethylamines, which are known to interact with monoamine neurotransmitters in the brain.
Pharmacology
The pharmacological profile of 6-APBT is not well-documented, but it is believed to act as a serotonin-norepinephrine-dopamine releasing agent (SNDRA). This means that it may increase the levels of these neurotransmitters in the synaptic cleft by promoting their release from presynaptic neurons. Such activity is typical of compounds that have stimulant and empathogenic effects, similar to those of MDMA and other related substances.
Potential Effects
While specific studies on 6-APBT are limited, its structural similarity to other benzothiophene derivatives suggests it may produce effects such as increased euphoria, stimulation, and empathy. However, the safety profile, potential for neurotoxicity, and long-term effects of 6-APBT remain largely unknown, necessitating caution in its use.
Legal Status
The legal status of 6-APBT varies by country. In some jurisdictions, it may be classified as a controlled substance due to its potential psychoactive effects and structural similarity to other regulated compounds. Researchers and users should be aware of the legal implications of possessing or distributing 6-APBT in their respective regions.
Synthesis
The synthesis of 6-APBT involves the chemical modification of benzothiophene derivatives. The process typically includes the introduction of an amino group to the propyl side chain, which can be achieved through various organic synthesis techniques. Detailed synthetic pathways are generally available in specialized chemical literature and require expertise in organic chemistry.
Related Compounds
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Contributors: Prab R. Tumpati, MD