5-Carboxamidotryptamine
5-Carboxamidotryptamine
5-Carboxamidotryptamine (5-CT) is a chemical compound that acts as a potent agonist at several serotonin receptor subtypes. It is primarily used in scientific research to study the function of serotonin receptors in the central nervous system.
Chemical Properties
5-Carboxamidotryptamine is a derivative of tryptamine, a naturally occurring monoamine alkaloid. The compound is characterized by the presence of a carboxamide group attached to the indole ring of tryptamine. This modification enhances its affinity for serotonin receptors, making it a valuable tool in pharmacological studies.
Mechanism of Action
5-CT acts as an agonist at multiple serotonin receptor subtypes, including 5-HT1A, 5-HT1B, and 5-HT7 receptors. By binding to these receptors, 5-CT can mimic the effects of serotonin, a key neurotransmitter involved in regulating mood, anxiety, and other physiological processes.
Applications in Research
In research settings, 5-Carboxamidotryptamine is used to:
- Investigate the role of serotonin receptors in various physiological and pathological processes.
- Study the effects of serotonin receptor activation on neurotransmission and neuroplasticity.
- Explore potential therapeutic targets for disorders such as depression, anxiety, and schizophrenia.
Safety and Handling
As with many research chemicals, 5-CT should be handled with care. It is important to follow appropriate safety protocols, including the use of personal protective equipment and proper storage conditions, to prevent accidental exposure.
Related Pages
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Contributors: Prab R. Tumpati, MD