Methotrexate-induced papular eruption
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Methotrexate-induced papular eruption appears in patients being treated with methotrexate, such as those with rheumatic disease, presenting with erythematous indurated papules, usually located on the proximal extremities.<ref name="Andrews">James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. Page 181. ISBN 0-7216-2921-0.</ref>
It has been suggested that it may represent a cutaneous small-vessel vasculitis.<ref>,
Methotrexate-induced papular eruption following treatment of psoriasis, Ann Pharmacother, Vol. 42(Issue: 1), pp. 138–41, DOI: 10.1345/aph.1K271, PMID: 18094347,</ref>
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