Ovarian hyperstimulation syndrome: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name                    = Ovarian hyperstimulation syndrome
| image                  = [[File:Vaginal_ultrasonography_in_OHSS_-_sagittal.png|250px]]
| caption                = Vaginal ultrasonography in OHSS
| field                  = [[Reproductive endocrinology]]
| synonyms                = OHSS
| symptoms                = Abdominal pain, bloating, nausea, vomiting, diarrhea, rapid weight gain
| complications          = [[Thromboembolism]], [[kidney failure]], [[ovarian torsion]], [[ascites]], [[pleural effusion]]
| onset                  = Within 10 days of [[ovulation induction]]
| duration                = Days to weeks
| causes                  = [[Fertility medication]]
| risks                  = [[Polycystic ovary syndrome]], high dose of [[gonadotropins]], previous OHSS
| diagnosis              = Based on symptoms and [[ultrasound]]
| differential            = [[Ectopic pregnancy]], [[ovarian cyst]], [[appendicitis]]
| prevention              = Using lower doses of fertility drugs, [[coasting]], [[GnRH antagonist]] protocol
| treatment              = Supportive care, [[paracentesis]], [[intravenous fluids]]
| medication              = [[Cabergoline]], [[albumin]]
| prognosis              = Generally good with treatment
| frequency              = 1-10% of women undergoing [[in vitro fertilization]]
}}
'''Ovarian hyperstimulation syndrome''' (OHSS) is a medical condition that can occur in some women who take fertility medication to stimulate egg growth, and in severe cases, it can be life threatening.
'''Ovarian hyperstimulation syndrome''' (OHSS) is a medical condition that can occur in some women who take fertility medication to stimulate egg growth, and in severe cases, it can be life threatening.
== Causes ==
== Causes ==
OHSS is caused by an over-response to [[fertility drugs]], especially those used during [[in vitro fertilization]] (IVF). These drugs stimulate the ovaries to produce multiple eggs. When the ovaries are overstimulated, they can swell and leak fluid into the body.
OHSS is caused by an over-response to [[fertility drugs]], especially those used during [[in vitro fertilization]] (IVF). These drugs stimulate the ovaries to produce multiple eggs. When the ovaries are overstimulated, they can swell and leak fluid into the body.
== Symptoms ==
== Symptoms ==
Symptoms of OHSS can range from mild to severe and may include:
Symptoms of OHSS can range from mild to severe and may include:
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* Rapid weight gain
* Rapid weight gain
* Difficulty breathing
* Difficulty breathing
== Diagnosis ==
== Diagnosis ==
OHSS is diagnosed based on a woman's symptoms and physical findings. A [[pelvic ultrasound]] may be used to assess the size of the ovaries and the amount of fluid in the abdomen. Blood tests may also be done to measure the levels of certain hormones.
OHSS is diagnosed based on a woman's symptoms and physical findings. A [[pelvic ultrasound]] may be used to assess the size of the ovaries and the amount of fluid in the abdomen. Blood tests may also be done to measure the levels of certain hormones.
== Treatment ==
== Treatment ==
Treatment for OHSS may include:
Treatment for OHSS may include:
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* Monitoring of symptoms
* Monitoring of symptoms
* In severe cases, hospitalization may be required for monitoring and treatment of complications.
* In severe cases, hospitalization may be required for monitoring and treatment of complications.
== Prevention ==
== Prevention ==
Prevention strategies may include using lower doses of fertility drugs and closely monitoring the response of the ovaries during fertility treatment.
Prevention strategies may include using lower doses of fertility drugs and closely monitoring the response of the ovaries during fertility treatment.
== See also ==
== See also ==
* [[In vitro fertilization]]
* [[In vitro fertilization]]
* [[Fertility drugs]]
* [[Fertility drugs]]
* [[Pelvic ultrasound]]
* [[Pelvic ultrasound]]
[[Category:Women's health]]
[[Category:Women's health]]
[[Category:Reproductive health]]
[[Category:Reproductive health]]
[[Category:Endocrine disorders]]
[[Category:Endocrine disorders]]
{{stub}}
{{stub}}
<gallery>
File:Vaginal_ultrasonography_in_OHSS_-_sagittal.png|Ovarian hyperstimulation syndrome
File:Vaginal_ultrasonography_in_mild_ovarian_hyperstimulation_syndrome_-_sagittal.jpg|Mild ovarian hyperstimulation syndrome
</gallery>

Latest revision as of 05:00, 6 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics

Ovarian hyperstimulation syndrome
Synonyms OHSS
Pronounce N/A
Specialty N/A
Symptoms Abdominal pain, bloating, nausea, vomiting, diarrhea, rapid weight gain
Complications Thromboembolism, kidney failure, ovarian torsion, ascites, pleural effusion
Onset Within 10 days of ovulation induction
Duration Days to weeks
Types N/A
Causes Fertility medication
Risks Polycystic ovary syndrome, high dose of gonadotropins, previous OHSS
Diagnosis Based on symptoms and ultrasound
Differential diagnosis Ectopic pregnancy, ovarian cyst, appendicitis
Prevention Using lower doses of fertility drugs, coasting, GnRH antagonist protocol
Treatment Supportive care, paracentesis, intravenous fluids
Medication Cabergoline, albumin
Prognosis Generally good with treatment
Frequency 1-10% of women undergoing in vitro fertilization
Deaths N/A


Ovarian hyperstimulation syndrome (OHSS) is a medical condition that can occur in some women who take fertility medication to stimulate egg growth, and in severe cases, it can be life threatening.

Causes[edit]

OHSS is caused by an over-response to fertility drugs, especially those used during in vitro fertilization (IVF). These drugs stimulate the ovaries to produce multiple eggs. When the ovaries are overstimulated, they can swell and leak fluid into the body.

Symptoms[edit]

Symptoms of OHSS can range from mild to severe and may include:

Diagnosis[edit]

OHSS is diagnosed based on a woman's symptoms and physical findings. A pelvic ultrasound may be used to assess the size of the ovaries and the amount of fluid in the abdomen. Blood tests may also be done to measure the levels of certain hormones.

Treatment[edit]

Treatment for OHSS may include:

  • Drinking plenty of fluids
  • Rest
  • Monitoring of symptoms
  • In severe cases, hospitalization may be required for monitoring and treatment of complications.

Prevention[edit]

Prevention strategies may include using lower doses of fertility drugs and closely monitoring the response of the ovaries during fertility treatment.

See also[edit]

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