Basophilia: Difference between revisions
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[[File:Hem1Basophile.jpg| | {{SI}} | ||
{{Infobox medical condition | |||
| name = Basophilia | |||
| image = [[File:Hem1Basophile.jpg|thumb|Basophil under a microscope]] | |||
| caption = Basophil under a microscope | |||
| field = [[Hematology]] | |||
| symptoms = [[Fatigue (medical)|Fatigue]], [[itching]], [[rash]], [[abdominal pain]] | |||
| complications = [[Anaphylaxis]], [[chronic myeloid leukemia]] | |||
| onset = Varies depending on underlying cause | |||
| duration = Varies | |||
| causes = [[Allergic reaction]], [[chronic inflammation]], [[myeloproliferative disorders]] | |||
| risks = [[Allergies]], [[autoimmune diseases]], [[infections]] | |||
| diagnosis = [[Complete blood count]], [[bone marrow biopsy]] | |||
| differential = [[Eosinophilia]], [[leukocytosis]], [[lymphocytosis]] | |||
| treatment = Treating underlying cause, [[antihistamines]], [[corticosteroids]] | |||
| medication = [[Antihistamines]], [[corticosteroids]] | |||
| frequency = Rare | |||
}} | |||
'''Basophilia''' is a condition characterized by an excessive number of [[basophils]] in the [[blood]]. Basophils are a type of [[white blood cell]] (WBC) that play a crucial role in the body's immune response by fighting off infections and releasing chemicals such as [[histamine]] and [[heparin]] during allergic reactions and inflammation. Basophilia can be an indicator of various health conditions, ranging from mild allergic reactions to more serious diseases such as [[chronic myelogenous leukemia]] (CML). | |||
==Causes== | ==Causes== | ||
Basophilia can be caused by a variety of factors and conditions, including: | Basophilia can be caused by a variety of factors and conditions, including: | ||
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* [[Hematologic diseases]]: Blood disorders, particularly [[chronic myelogenous leukemia]] (CML), are known to cause basophilia. | * [[Hematologic diseases]]: Blood disorders, particularly [[chronic myelogenous leukemia]] (CML), are known to cause basophilia. | ||
* [[Endocrine disorders]]: Conditions affecting the endocrine system, such as [[hypothyroidism]], can lead to an increase in basophils. | * [[Endocrine disorders]]: Conditions affecting the endocrine system, such as [[hypothyroidism]], can lead to an increase in basophils. | ||
==Symptoms== | ==Symptoms== | ||
The symptoms of basophilia depend on the underlying cause of the condition. In many cases, individuals may not exhibit any symptoms directly related to an increase in basophils. However, symptoms related to the underlying condition, such as itching or inflammation from allergies, pain and swelling from infections, or fatigue and weight loss from leukemia, may be present. | The symptoms of basophilia depend on the underlying cause of the condition. In many cases, individuals may not exhibit any symptoms directly related to an increase in basophils. However, symptoms related to the underlying condition, such as itching or inflammation from allergies, pain and swelling from infections, or fatigue and weight loss from leukemia, may be present. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of basophilia involves a complete [[blood count]] (CBC) with a differential to measure the number of each type of white blood cell present in the blood. An elevated basophil count is typically considered to be above 100 basophils per microliter of blood, but this can vary depending on the laboratory's reference range. | Diagnosis of basophilia involves a complete [[blood count]] (CBC) with a differential to measure the number of each type of white blood cell present in the blood. An elevated basophil count is typically considered to be above 100 basophils per microliter of blood, but this can vary depending on the laboratory's reference range. | ||
==Treatment== | ==Treatment== | ||
Treatment for basophilia focuses on addressing the underlying cause of the condition. For allergic reactions, antihistamines or corticosteroids may be prescribed to reduce symptoms. Infections may require antibiotics or antiparasitic medications. For hematologic diseases like CML, treatment options may include chemotherapy, targeted therapy, or stem cell transplantation. | Treatment for basophilia focuses on addressing the underlying cause of the condition. For allergic reactions, antihistamines or corticosteroids may be prescribed to reduce symptoms. Infections may require antibiotics or antiparasitic medications. For hematologic diseases like CML, treatment options may include chemotherapy, targeted therapy, or stem cell transplantation. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for individuals with basophilia varies widely and depends on the underlying cause of the condition. For those with allergies or infections, the prognosis is generally good with appropriate treatment. However, for individuals with chronic conditions or hematologic diseases, the outlook depends on the specific disease and its stage at diagnosis. | The prognosis for individuals with basophilia varies widely and depends on the underlying cause of the condition. For those with allergies or infections, the prognosis is generally good with appropriate treatment. However, for individuals with chronic conditions or hematologic diseases, the outlook depends on the specific disease and its stage at diagnosis. | ||
[[Category:Blood disorders]] | [[Category:Blood disorders]] | ||
[[Category:Immune system disorders]] | [[Category:Immune system disorders]] | ||
{{medicine-stub}} | {{medicine-stub}} | ||
Latest revision as of 23:20, 5 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Basophilia | |
|---|---|
 | |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Fatigue, itching, rash, abdominal pain |
| Complications | Anaphylaxis, chronic myeloid leukemia |
| Onset | Varies depending on underlying cause |
| Duration | Varies |
| Types | N/A |
| Causes | Allergic reaction, chronic inflammation, myeloproliferative disorders |
| Risks | Allergies, autoimmune diseases, infections |
| Diagnosis | Complete blood count, bone marrow biopsy |
| Differential diagnosis | Eosinophilia, leukocytosis, lymphocytosis |
| Prevention | N/A |
| Treatment | Treating underlying cause, antihistamines, corticosteroids |
| Medication | Antihistamines, corticosteroids |
| Prognosis | N/A |
| Frequency | Rare |
| Deaths | N/A |
Basophilia is a condition characterized by an excessive number of basophils in the blood. Basophils are a type of white blood cell (WBC) that play a crucial role in the body's immune response by fighting off infections and releasing chemicals such as histamine and heparin during allergic reactions and inflammation. Basophilia can be an indicator of various health conditions, ranging from mild allergic reactions to more serious diseases such as chronic myelogenous leukemia (CML).
Causes[edit]
Basophilia can be caused by a variety of factors and conditions, including:
- Allergic reactions: The body's response to allergens can lead to an increase in basophils.
- Infections: Certain infections, especially those caused by parasites, can trigger basophilia.
- Inflammatory conditions: Diseases such as rheumatoid arthritis and inflammatory bowel disease (IBD) can cause elevated basophil levels.
- Hematologic diseases: Blood disorders, particularly chronic myelogenous leukemia (CML), are known to cause basophilia.
- Endocrine disorders: Conditions affecting the endocrine system, such as hypothyroidism, can lead to an increase in basophils.
Symptoms[edit]
The symptoms of basophilia depend on the underlying cause of the condition. In many cases, individuals may not exhibit any symptoms directly related to an increase in basophils. However, symptoms related to the underlying condition, such as itching or inflammation from allergies, pain and swelling from infections, or fatigue and weight loss from leukemia, may be present.
Diagnosis[edit]
Diagnosis of basophilia involves a complete blood count (CBC) with a differential to measure the number of each type of white blood cell present in the blood. An elevated basophil count is typically considered to be above 100 basophils per microliter of blood, but this can vary depending on the laboratory's reference range.
Treatment[edit]
Treatment for basophilia focuses on addressing the underlying cause of the condition. For allergic reactions, antihistamines or corticosteroids may be prescribed to reduce symptoms. Infections may require antibiotics or antiparasitic medications. For hematologic diseases like CML, treatment options may include chemotherapy, targeted therapy, or stem cell transplantation.
Prognosis[edit]
The prognosis for individuals with basophilia varies widely and depends on the underlying cause of the condition. For those with allergies or infections, the prognosis is generally good with appropriate treatment. However, for individuals with chronic conditions or hematologic diseases, the outlook depends on the specific disease and its stage at diagnosis.
