Hypernatremia

Hypernatremia is a common electrolyte problem and is defined as a rise in serum sodium concentration to a value exceeding 145 mmol/L. It is strictly defined as a hyperosmolar condition caused by a decrease in total body water (TBW) relative to electrolyte content. Hypernatremia can be caused by various conditions and can lead to a wide range of symptoms from lethargy and irritability to seizures and coma.

Causes

Hypernatremia can be caused by a variety of conditions, including:

• Dehydration
• Diabetes insipidus
• Hyperaldosteronism
• Cushing's syndrome
• Kidney disease
• Hypertonic saline
• Medications such as diuretics, steroids, and some antibiotics

Symptoms

Symptoms of hypernatremia can vary depending on the severity of the condition. They can include:

• Thirst
• Dry mouth
• Lethargy
• Irritability
• Seizures
• Coma

Diagnosis

Diagnosis of hypernatremia is typically made through a blood test that measures the level of sodium in the blood. Other tests may be done to determine the underlying cause of the condition.

Treatment

Treatment of hypernatremia typically involves treating the underlying cause of the condition, as well as measures to lower the sodium level in the blood. This can include:

• Intravenous fluids
• Medications to manage symptoms and treat underlying conditions
• Dietary changes to reduce sodium intake

See also

• Hyponatremia
• Electrolyte imbalance
• Water-electrolyte imbalance

References

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