Flavanonol: Difference between revisions

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'''Flavanonol''' is a type of [[flavonoid]], a class of [[phytochemical]]s known for their potential health benefits. Flavanonols are a subclass of flavonoids and are distinguished by the presence of a 3-hydroxyflavan backbone. They are found in a variety of [[plant]]s and [[fruit]]s, and are responsible for some of the colors and flavors we associate with these foods.
{{DISPLAYTITLE:Flavanonol}}


== Structure and Classification ==
== Overview ==
[[File:Flavanonol_num.svg|thumb|right|Chemical structure of a flavanonol]]
'''Flavanonols''' are a class of [[flavonoids]], which are a diverse group of [[phytonutrients]] (plant chemicals) found in almost all fruits and vegetables. Flavanonols are characterized by their unique chemical structure, which includes a 3-hydroxyflavanone backbone. They are known for their potential health benefits, including antioxidant, anti-inflammatory, and anti-cancer properties.


Flavanonols are characterized by the structure of their carbon skeleton, which consists of two [[phenyl]] groups (A and B) and a heterocyclic ring (C). This structure is common to all flavonoids, but flavanonols are specifically characterized by the presence of a hydroxyl group at the 3-position of the C ring.
== Chemical Structure ==
Flavanonols are structurally similar to [[flavanones]], but they differ by the presence of a hydroxyl group at the 3-position of the C-ring. This structural difference is crucial as it influences the biological activity of these compounds. The basic structure of flavanonols consists of two aromatic rings (A and B) and a heterocyclic ring (C) that contains the 3-hydroxy group.


Flavanonols can be further classified based on the number and position of additional hydroxyl groups. For example, [[taxifolin]] is a flavanonol with hydroxyl groups at the 3', 4', and 5' positions.
== Biosynthesis ==
Flavanonols are synthesized in plants through the [[phenylpropanoid pathway]], which is a major metabolic route for the production of flavonoids. The pathway begins with the amino acid [[phenylalanine]], which is converted into various intermediates, eventually leading to the formation of flavanonols. Enzymes such as [[chalcone synthase]] and [[flavanone 3-hydroxylase]] play key roles in this biosynthetic process.


== Sources ==
== Biological Functions ==
Flavanonols are known for their role in plant defense mechanisms. They contribute to the protection against [[ultraviolet radiation]], pathogens, and herbivores. In humans, flavanonols have been studied for their potential health benefits. They exhibit antioxidant properties, which help in neutralizing [[free radicals]] and reducing oxidative stress. Additionally, flavanonols have been shown to possess anti-inflammatory and anti-cancer activities, making them of interest in [[nutraceutical]] and [[pharmaceutical]] research.


Flavanonols are found in a variety of plant-based foods. Some of the richest sources include:
== Dietary Sources ==
 
Flavanonols are found in a variety of fruits and vegetables. Common dietary sources include [[onions]], [[kale]], [[broccoli]], [[apples]], and [[berries]]. The concentration of flavanonols can vary depending on the plant species, growing conditions, and processing methods.
* [[Apple]]s
* [[Berry|Berries]]
* [[Grape]]s
* [[Tea]]
* [[Cocoa]]


== Health Benefits ==
== Health Benefits ==
Research suggests that a diet rich in flavanonols may contribute to the prevention of chronic diseases such as [[cardiovascular disease]], [[cancer]], and [[neurodegenerative disorders]]. Their antioxidant properties help in protecting cells from damage, while their anti-inflammatory effects can reduce the risk of chronic inflammation-related diseases.


Research has suggested that flavanonols may have a number of potential health benefits. These include:
== Related Pages ==
 
* [[Antioxidant]] activity: Like many flavonoids, flavanonols have been shown to have antioxidant properties, which means they can help protect the body's cells from damage by free radicals.
* [[Anti-inflammatory]] effects: Some studies have suggested that flavanonols may help reduce inflammation in the body.
* Cardiovascular health: There is some evidence that flavanonols may help improve cardiovascular health by improving blood flow and reducing the risk of blood clots.
 
== See Also ==
 
* [[Flavonoid]]
* [[Flavonoid]]
* [[Phytochemical]]
* [[Antioxidant]]
* [[Antioxidant]]
* [[Anti-inflammatory]]
* [[Phenylpropanoid pathway]]
* [[Nutraceutical]]


[[Category:Flavonoids]]
[[Category:Flavonoids]]
[[Category:Phytochemicals]]
[[Category:Nutrition]]
[[Category:Health]]
{{medicine-stub}}

Latest revision as of 03:34, 13 February 2025


Overview[edit]

Chemical structure of a flavanonol

Flavanonols are a class of flavonoids, which are a diverse group of phytonutrients (plant chemicals) found in almost all fruits and vegetables. Flavanonols are characterized by their unique chemical structure, which includes a 3-hydroxyflavanone backbone. They are known for their potential health benefits, including antioxidant, anti-inflammatory, and anti-cancer properties.

Chemical Structure[edit]

Flavanonols are structurally similar to flavanones, but they differ by the presence of a hydroxyl group at the 3-position of the C-ring. This structural difference is crucial as it influences the biological activity of these compounds. The basic structure of flavanonols consists of two aromatic rings (A and B) and a heterocyclic ring (C) that contains the 3-hydroxy group.

Biosynthesis[edit]

Flavanonols are synthesized in plants through the phenylpropanoid pathway, which is a major metabolic route for the production of flavonoids. The pathway begins with the amino acid phenylalanine, which is converted into various intermediates, eventually leading to the formation of flavanonols. Enzymes such as chalcone synthase and flavanone 3-hydroxylase play key roles in this biosynthetic process.

Biological Functions[edit]

Flavanonols are known for their role in plant defense mechanisms. They contribute to the protection against ultraviolet radiation, pathogens, and herbivores. In humans, flavanonols have been studied for their potential health benefits. They exhibit antioxidant properties, which help in neutralizing free radicals and reducing oxidative stress. Additionally, flavanonols have been shown to possess anti-inflammatory and anti-cancer activities, making them of interest in nutraceutical and pharmaceutical research.

Dietary Sources[edit]

Flavanonols are found in a variety of fruits and vegetables. Common dietary sources include onions, kale, broccoli, apples, and berries. The concentration of flavanonols can vary depending on the plant species, growing conditions, and processing methods.

Health Benefits[edit]

Research suggests that a diet rich in flavanonols may contribute to the prevention of chronic diseases such as cardiovascular disease, cancer, and neurodegenerative disorders. Their antioxidant properties help in protecting cells from damage, while their anti-inflammatory effects can reduce the risk of chronic inflammation-related diseases.

Related Pages[edit]