Poorly differentiated thyroid cancer: Difference between revisions
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Revision as of 22:37, 10 February 2025
| Poorly differentiated thyroid carcinoma | |
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| Synonyms | PDTC |
| Pronounce | |
| Field | |
| Symptoms | |
| Complications | |
| Onset | |
| Duration | |
| Types | |
| Causes | |
| Risks | |
| Diagnosis | |
| Differential diagnosis | |
| Prevention | |
| Treatment | |
| Medication | |
| Prognosis | |
| Frequency | |
| Deaths | |
Poorly differentiated thyroid carcinoma is malignant neoplasm of follicular cell origin showing intermediate histopathological patterns between differentiated and undifferentiated thyroid cancers.<ref>,
Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach., Am J Surg Pathol, 2007, Vol. 31(Issue: 8), pp. 1256–64, DOI: 10.1097/PAS.0b013e3180309e6a, PMID: 17667551,</ref>
Histopathology
- Presence of small cells with round nuclei and scant cytoplasm with a diffuse solid pattern
- Round or oval nests (insulae) or in trabeculae.
- Solid growth and presence of microfollicles, some of which contain dense colloid.
- Extrathyroidal extension and blood vessel invasion
- Foci of necrosis,
- Larger than 5 cm in greatest diameter at diagnosis
Epidemiology
- PDTC affects predominantly females about 55 years of age
References
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External links
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