Ureteral neoplasm
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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| Ureteral neoplasm | |
|---|---|
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Hematuria, flank pain, urinary tract infection |
| Complications | Hydronephrosis, renal failure |
| Onset | Typically in adults |
| Duration | Varies |
| Types | Transitional cell carcinoma, squamous cell carcinoma, adenocarcinoma |
| Causes | Smoking, chemical exposure, chronic inflammation |
| Risks | Smoking, family history, chronic urinary tract infections |
| Diagnosis | Cystoscopy, CT scan, MRI, biopsy |
| Differential diagnosis | Kidney stones, urinary tract infection, bladder cancer |
| Prevention | N/A |
| Treatment | Surgery, chemotherapy, radiation therapy |
| Medication | N/A |
| Prognosis | Depends on stage and type |
| Frequency | Rare |
| Deaths | N/A |
A ureteral neoplasm is a type of tumor that occurs in the ureter, the duct that carries urine from the kidney to the bladder. These neoplasms can be benign or malignant, with the latter being more common. Malignant ureteral neoplasms are often transitional cell carcinomas, similar to those found in the bladder.
Types
Ureteral neoplasms are classified based on their nature:
- Benign neoplasms: These are non-cancerous growths that do not spread to other parts of the body. Examples include fibromas and leiomyomas.
- Malignant neoplasms: These are cancerous tumors that can invade surrounding tissues and metastasize. The most common type is transitional cell carcinoma, but squamous cell carcinoma and adenocarcinoma can also occur.
Symptoms
Symptoms of ureteral neoplasms may include:
- Hematuria (blood in the urine)
- Flank pain
- Urinary tract infections
- Hydronephrosis (swelling of a kidney due to urine buildup)
Diagnosis
Diagnosis of ureteral neoplasms typically involves:
- Imaging studies such as CT scans or MRIs
- Cystoscopy and ureteroscopy to visually inspect the ureter
- Biopsy to obtain tissue samples for histological examination
Treatment
Treatment options depend on the type and stage of the neoplasm:
- Surgical removal: This is the primary treatment for localized tumors. Techniques include ureterectomy or nephroureterectomy.
- Chemotherapy and radiation therapy: These may be used for advanced or metastatic cancers.
- Endoscopic resection: Minimally invasive removal of tumors via endoscopy.
Prognosis
The prognosis for ureteral neoplasms varies based on the type and stage of the tumor. Early detection and treatment generally lead to better outcomes. Malignant tumors have a higher risk of recurrence and metastasis, affecting long-term survival rates.
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Contributors: Prab R. Tumpati, MD