Tzanck test

Tzanck Test

The Tzanck test (pronounced: /ˈzæŋk/), also known as Tzanck smear, is a medical diagnostic test used primarily to diagnose certain skin conditions. The test was named after the French dermatologist, Arnault Tzanck.

Etymology

The Tzanck test is named after Arnault Tzanck, a French dermatologist who first described the test in the early 20th century.

Procedure

The Tzanck test involves taking a sample of cells from the base of a skin lesion. This is done by scraping the lesion with a sterile instrument. The collected cells are then smeared onto a glass slide and stained with a special dye. The slide is then examined under a microscope to look for any abnormal cells.

Uses

The Tzanck test is primarily used to diagnose skin conditions caused by the herpes virus, such as herpes simplex and varicella zoster. It can also be used to diagnose other conditions such as pemphigus vulgaris and bullous pemphigoid.

Limitations

While the Tzanck test can be useful in diagnosing certain skin conditions, it does have its limitations. The test cannot differentiate between the different types of herpes viruses. Additionally, a negative result does not necessarily rule out a herpes infection.

Related Terms

• Herpes virus
• Herpes simplex
• Varicella zoster
• Pemphigus vulgaris
• Bullous pemphigoid

External links

• Medical encyclopedia article on Tzanck test
• Wikipedia's article - Tzanck test

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