Trabecular oedema

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Trabecular oedema
Synonyms	Trabecular edema
Pronounce	N/A
Specialty	N/A
Symptoms	Blurred vision, eye pain, halos around lights
Complications	Glaucoma, vision loss
Onset	Sudden or gradual
Duration	Variable
Types	N/A
Causes	Intraocular pressure changes, inflammation
Risks	Age, family history, eye surgery
Diagnosis	Ophthalmic examination, tonometry, gonioscopy
Differential diagnosis	Corneal edema, uveitis, acute angle-closure glaucoma
Prevention	Regular eye exams, managing risk factors
Treatment	Medications, laser therapy, surgery
Medication	N/A
Prognosis	Variable, depending on cause and treatment
Frequency	Rare
Deaths	N/A

Trabecular oedema refers to the accumulation of excess fluid within the trabecular bone, which is the spongy bone found at the ends of long bones and within the interior of vertebrae. This condition is often detected through imaging techniques such as magnetic resonance imaging (MRI) and is associated with various musculoskeletal disorders.

Pathophysiology

Trabecular oedema occurs when there is an increase in fluid within the bone marrow spaces of the trabecular bone. This can be due to a variety of causes, including trauma, inflammation, or degenerative changes. The increased fluid can lead to increased pressure within the bone, causing pain and discomfort.

Causes

Trauma

MRI of hip fracture showing trabecular oedema

Trauma is a common cause of trabecular oedema. Injuries such as fractures or bone contusions can lead to localized oedema as part of the body's inflammatory response. The oedema is often seen in conjunction with other signs of injury on imaging studies.

Osteoarthritis

Knee osteoarthritis illustration

In conditions like osteoarthritis, the degeneration of joint cartilage and underlying bone can lead to trabecular oedema. The increased mechanical stress on the bone due to cartilage loss can cause microfractures and subsequent fluid accumulation.

Inflammatory Conditions

Inflammatory conditions such as rheumatoid arthritis can also lead to trabecular oedema. The inflammation associated with these conditions can increase vascular permeability, leading to fluid leakage into the bone marrow spaces.

Symptoms

The primary symptom of trabecular oedema is pain, which is often localized to the affected area. The pain may be exacerbated by weight-bearing activities or movement. Swelling and tenderness may also be present.

Diagnosis

Knee effusion, often associated with trabecular oedema

Diagnosis of trabecular oedema is typically made using MRI, which can visualize the increased fluid content within the bone. MRI is preferred over other imaging modalities because it provides detailed images of soft tissues and bone marrow.

Treatment

Treatment of trabecular oedema focuses on addressing the underlying cause. For traumatic injuries, rest and immobilization may be recommended. In cases of osteoarthritis or inflammatory conditions, medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids may be used to reduce inflammation and pain.

Iloprost, a medication used in some cases

In some cases, medications like Iloprost may be used to improve blood flow and reduce oedema. Physical therapy may also be beneficial in restoring function and reducing pain.

Prognosis

The prognosis for trabecular oedema depends on the underlying cause. In cases of trauma, the oedema often resolves with appropriate treatment. In chronic conditions like osteoarthritis, management of symptoms and slowing disease progression are the primary goals.

See also

• Bone marrow edema
• Osteoarthritis
• Rheumatoid arthritis
• Magnetic resonance imaging