Toluic acid
Toluic acid refers to any of the three isomeric compounds of benzoic acid with a methyl group (CH3). The three isomers include ortho-toluic acid (o-toluic acid), meta-toluic acid (m-toluic acid), and para-toluic acid (p-toluic acid).
Chemical Structure and Properties
Toluic acids are aromatic compounds with a carboxylic acid group (-COOH) and a methyl group attached to the benzene ring. The position of the methyl group relative to the carboxylic acid group determines the type of toluic acid.
In o-toluic acid, the methyl and carboxylic acid groups are adjacent. In m-toluic acid, they are separated by one carbon atom, and in p-toluic acid, they are on opposite sides of the benzene ring.
Toluic acids are white, crystalline solids at room temperature. They are slightly soluble in water but dissolve readily in organic solvents such as ethanol, acetone, and diethyl ether.
Synthesis and Uses
Toluic acids can be synthesized by the oxidation of the corresponding toluene derivatives. They are used in the manufacture of dyes, resins, pharmaceuticals, and other organic compounds.
Safety and Environmental Impact
Toluic acids are irritants and can cause burns if they come into contact with the skin or eyes. They are also harmful if swallowed or inhaled.
In the environment, toluic acids can cause harm to aquatic life. They are not readily biodegradable and can accumulate in the environment.
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Contributors: Prab R. Tumpati, MD