Sodium fumarate
Sodium Fumarate
Sodium fumarate is the sodium salt of fumaric acid, an important compound in the Krebs cycle (also known as the citric acid cycle), which is a key metabolic pathway that unifies carbohydrate, fat, and protein metabolism. Sodium fumarate is used in various biochemical applications and as a food additive.
Chemical Properties
Sodium fumarate is a white crystalline powder that is highly soluble in water. It is the sodium salt form of fumaric acid, which is a dicarboxylic acid. The chemical formula for sodium fumarate is C_H_NaO_.
Biological Role
In the Krebs cycle, fumarate is formed by the oxidation of succinate by the enzyme succinate dehydrogenase. Fumarate is then hydrated to malate by the enzyme fumarase. This cycle is crucial for the production of adenosine triphosphate (ATP), which is the energy currency of the cell.
Uses
Sodium fumarate is used in the food industry as an acidity regulator and as a flavoring agent. It is also used in the pharmaceutical industry for its potential therapeutic effects. In biochemistry, sodium fumarate is used in studies of the Krebs cycle and other metabolic pathways.
Related Compounds
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Contributors: Prab R. Tumpati, MD
