Retinal vasculitis

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Retinal vasculitis
Anatomy of the human eye
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Blurred vision, floaters, photopsia, scotoma
Complications Vision loss, retinal detachment, macular edema
Onset Variable
Duration Chronic
Types N/A
Causes Autoimmune disorders, infections, idiopathic
Risks Autoimmune diseases, infections, genetic predisposition
Diagnosis Fluorescein angiography, optical coherence tomography, clinical examination
Differential diagnosis Uveitis, retinal vein occlusion, diabetic retinopathy
Prevention N/A
Treatment Corticosteroids, immunosuppressive drugs, biologic agents
Medication N/A
Prognosis Variable, depends on underlying cause and treatment
Frequency Rare
Deaths N/A


Retinal Vasculitis is an inflammatory disease that affects the blood vessels of the retina in the eye, leading to various degrees of visual impairment. This condition can be an isolated ocular issue or part of a systemic disease affecting multiple organs. The inflammation can lead to complications such as retinal ischemia, neovascularization, and even retinal detachment, making early diagnosis and treatment crucial for preserving vision.

Causes and Risk Factors

Retinal vasculitis can be caused by a wide array of conditions, including autoimmune diseases such as Systemic Lupus Erythematosus (SLE) and Behçet's Disease, infectious diseases like Tuberculosis and Syphilis, and idiopathic conditions, where the cause remains unknown. Genetic predisposition and environmental factors may also play a role in the development of this condition.

Symptoms

Common symptoms of retinal vasculitis include:

  • Blurred vision
  • Floaters in the vision
  • Loss of peripheral vision
  • Sudden loss of vision in one or both eyes
  • Pain and redness in the eye

Diagnosis

Diagnosis of retinal vasculitis involves a comprehensive eye examination, including:

  • Fundus photography to capture detailed images of the retina
  • Fluorescein angiography to highlight the blood vessels in the eye
  • Optical coherence tomography (OCT) to obtain cross-sectional images of the retina

Blood tests, chest X-rays, and other imaging studies may also be conducted to identify any systemic diseases associated with the condition.

Treatment

Treatment of retinal vasculitis focuses on controlling the inflammation and preventing further damage to the retina. This may include:

  • Corticosteroids (either systemic or injected directly into the eye)
  • Immunosuppressive drugs for more severe cases or when systemic diseases are involved
  • Anti-VEGF (Vascular Endothelial Growth Factor) therapy for cases with neovascularization
  • Laser photocoagulation therapy to treat areas of retinal ischemia

Prognosis

The prognosis for patients with retinal vasculitis varies depending on the underlying cause, the severity of the inflammation, and the promptness of treatment initiation. Early detection and treatment are crucial for a favorable outcome and to minimize the risk of permanent vision loss.

Prevention

Preventive measures for retinal vasculitis are largely dependent on controlling the underlying conditions that may lead to the disease. Regular medical check-ups, maintaining a healthy lifestyle, and promptly addressing any symptoms of eye discomfort or vision changes can help in early detection and treatment.

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Contributors: Prab R. Tumpati, MD