Phagolysosome

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Phagolysosome

Phagolysosome (pronounced: fag-o-ly-so-some) is a cytoplasmic body formed by the fusion of a phagosome and a lysosome in a process during phagocytosis.

Etymology

The term "Phagolysosome" is derived from the Greek words "phagein" meaning "to eat", "lysis" meaning "loosening", and "soma" meaning "body".

Definition

A phagolysosome is a vesicle formed within a cell in the process of phagocytosis by the fusion of the membrane of a phagosome with that of a lysosome. The lysosome contributes digestive enzymes which help in the breakdown of the ingested material inside the phagosome.

Function

The primary function of a phagolysosome is to degrade or break down foreign particles or microorganisms that have been engulfed by a cell during the process of phagocytosis. The lysosomal enzymes within the phagolysosome break down the engulfed material into simpler substances that can be used by the cell.

Related Terms

  • Phagocytosis: The process by which cells engulf particles to form a phagosome.
  • Phagosome: A vesicle formed around a particle engulfed by a cell during phagocytosis.
  • Lysosome: A cell organelle containing enzymes that digest particles and that can digest the cell itself if it dies.
  • Endocytosis: The process by which cells absorb molecules by engulfing them.

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