Metralindole

From WikiMD's medical encyclopedia

Metralindole is a psychotropic drug used in the treatment of various psychiatric disorders. It is classified as a reversible inhibitor of monoamine oxidase A (RIMA), a type of enzyme that breaks down monoamines in the body. Metralindole is also known to have antidepressant and anxiolytic effects.

Pharmacology

Metralindole works by inhibiting the action of monoamine oxidase A, an enzyme that is responsible for breaking down monoamines in the body. Monoamines include neurotransmitters such as serotonin, norepinephrine, and dopamine, which play crucial roles in mood regulation. By inhibiting the breakdown of these neurotransmitters, Metralindole increases their levels in the brain, which can help alleviate symptoms of depression and anxiety.

Clinical Use

Metralindole is used in the treatment of various psychiatric disorders, including major depressive disorder, anxiety disorders, and obsessive-compulsive disorder. It is also used in the treatment of panic disorder and social phobia.

Side Effects

Like all medications, Metralindole can cause side effects. Common side effects include nausea, dizziness, insomnia, and dry mouth. In rare cases, Metralindole can cause serotonin syndrome, a potentially life-threatening condition characterized by agitation, hallucinations, rapid heartbeat, and high body temperature.

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