Melancholia

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Melancholia
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Persistent sadness, anhedonia, fatigue, insomnia, appetite changes
Complications	Major depressive disorder, suicidal ideation
Onset	Typically in adulthood
Duration	Can be chronic or episodic
Types	N/A
Causes	Genetic predisposition, environmental factors, neurochemical imbalances
Risks	Family history, stressful life events, chronic illness
Diagnosis	Clinical assessment, DSM-5 criteria
Differential diagnosis	Bipolar disorder, dysthymia, anxiety disorders
Prevention	N/A
Treatment	Psychotherapy, antidepressant medication, electroconvulsive therapy
Medication	N/A
Prognosis	Varies; can be managed with treatment
Frequency	Common
Deaths	N/A

Melancholia is a psychological disorder characterized by severe depression, extreme despair, and a lack of pleasure in most activities. The term "melancholia" is derived from the Greek words "melas" (black) and "khole" (bile), reflecting the ancient belief that it was caused by an excess of black bile in the body.

History

The concept of melancholia has a long history, dating back to Hippocrates, who described it as a distinct disease with specific physical and mental symptoms. He believed that it was caused by an imbalance of the four humors in the body, specifically an excess of black bile. This theory was widely accepted until the 19th century, when it was replaced by more modern theories of psychiatry. In the Middle Ages, melancholia was associated with demonic possession, and treatments often involved exorcism and other religious rituals. In the Renaissance, it was seen as a sign of genius and creativity, and many famous artists and writers were said to suffer from it. In the 20th century, the term "melancholia" was largely replaced by "depression" in the medical literature, although it is still used in some contexts to refer to a specific subtype of depression characterized by severe symptoms and a poor response to treatment.

Symptoms

The symptoms of melancholia can vary widely, but they typically include a persistent feeling of sadness or despair, a lack of interest in activities that were once enjoyable, and a reduced ability to function in daily life. Other symptoms can include changes in appetite or weight, sleep disturbances, fatigue, feelings of worthlessness or guilt, difficulty concentrating, and thoughts of death or suicide.

Treatment

The treatment of melancholia typically involves a combination of psychotherapy and medication. Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs), can be effective in reducing symptoms. Psychotherapy, particularly cognitive behavioral therapy (CBT), can also be helpful in changing negative thought patterns and improving coping skills.

Melancholia gallery

• 

  Albrecht Dürer - Melencolia I

• 

  Robert Burton's Anatomy of Melancholy, 1626, 2nd edition

• 

  Ch. Boirau, "The Spleen" ("Melancholy")

• 

  John Donne

• 

  Melancholy - Castiglione

• 

  La Meditazione by Domenico Fetti, 1618

See also

• Depression (mood)
• Bipolar disorder
• Major depressive disorder
• Dysthymia

This article is a medical stub. You can help WikiMD by expanding it!
Most recent articles Ongoing trials	Wikipedia