Kisspeptin
Kisspeptin
Kisspeptin (pronounced: kis-pep-tin), also known as metastin, is a protein that in humans is encoded by the KISS1 gene.
Etymology
The name "kisspeptin" is derived from the Hershey's Kisses chocolate, as the gene was discovered in Hershey, Pennsylvania.
Function
Kisspeptin is a potent stimulator of gonadotropin-releasing hormone (GnRH) secretion and is essential for fertility. It plays a key role in the regulation of the hypothalamic-pituitary-gonadal axis, which controls sexual maturation and fertility.
Clinical significance
Mutations in the KISS1 gene have been associated with hypogonadotropic hypogonadism, a condition characterized by delayed or absent puberty and infertility.
Related terms
- KISS1R: The receptor for kisspeptin, also known as GPR54.
- Gonadotropin-releasing hormone (GnRH): A hormone that stimulates the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.
- Hypothalamic-pituitary-gonadal axis (HPG axis): A hormonal system that plays a key role in reproduction and sexual development.
See also
External links
- Medical encyclopedia article on Kisspeptin
- Wikipedia's article - Kisspeptin
This WikiMD article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski