Interphase

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Interphase

Interphase (/ˈɪntərˌfeɪz/) is a phase of the cell cycle in which a typical cell spends the majority of its life. During interphase, the cell copies its DNA in preparation for mitosis. Interphase is the 'daily living' or metabolic phase of the cell, in which the cell obtains nutrients and metabolizes them, grows, reads its DNA, and conducts other "normal" cell functions.

Etymology

The term "interphase" was coined in the late 19th century from the Latin inter- meaning "between" and -phase derived from the Greek phásis meaning "appearance". It refers to the phase in the cell cycle that is between two successive M phases.

Stages of Interphase

Interphase is divided into three stages:

  • G1 phase - The cell grows and functions normally. During this time, a high amount of protein synthesis occurs and the cell grows (to about double its original size) - more organelles are produced and the volume of the cytoplasm increases. If the cell is not to divide again, it will enter G0 phase.
  • S phase - The cell synthesizes a replica of the genome. This synthesis is carried out in a systematic and precise fashion, to ensure that the replication is exact and not a single DNA base is changed.
  • G2 phase - The cell continues to grow and to prepare for division. The cell checks for DNA errors and repairs them.

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