Ibuprofen/famotidine
Ibuprofen/Famotidine
Ibuprofen/famotidine is a combination medication that includes ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), and famotidine, a histamine-2 blocker. This combination is used to reduce the risk of ulcers in the stomach or intestines in people who are taking ibuprofen for arthritis.
Composition
The medication is composed of two active ingredients: ibuprofen and famotidine. Ibuprofen is a NSAID that works by reducing hormones that cause inflammation and pain in the body. Famotidine is a histamine-2 blocker that works by decreasing the amount of acid the stomach produces.
Indications
Ibuprofen/famotidine is indicated for the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis and to decrease the risk of developing upper gastrointestinal ulcers.
Contraindications
This medication is contraindicated in patients with known hypersensitivity to ibuprofen or famotidine. It should not be used in patients who have experienced asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs.
Side Effects
Common side effects of ibuprofen/famotidine include nausea, diarrhea, constipation, dizziness, and headache. Serious side effects may include heart attack or stroke, bleeding, ulcers, and anemia.
Interactions
Ibuprofen/famotidine may interact with other drugs such as warfarin, lithium, methotrexate, and corticosteroids. It is important to inform the healthcare provider of all medications being taken.
Dosage
The dosage of ibuprofen/famotidine is based on the patient's medical condition and response to treatment. It is usually taken as directed by the healthcare provider.
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Contributors: Prab R. Tumpati, MD