Hypouricemia

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Hypouricemia
Uric acid
Synonyms	Hypouricaemia
Pronounce	N/A
Specialty	N/A
Symptoms	Often asymptomatic, may include fatigue, joint pain, muscle weakness
Complications	Kidney stones, renal failure
Onset	Any age
Duration	Chronic
Types	N/A
Causes	Genetic disorders, medications, dietary factors, renal tubular dysfunction
Risks	Gout, cardiovascular disease
Diagnosis	Blood test for serum uric acid levels
Differential diagnosis	Hyperuricemia, gout, renal disease
Prevention	N/A
Treatment	Address underlying cause, dietary modification, medication
Medication	N/A
Prognosis	N/A
Frequency	Rare
Deaths	N/A

Hypouricemia is a condition characterized by abnormally low levels of uric acid in the blood. It is often associated with other medical conditions, such as renal tubular acidosis, Fanconi syndrome, and Wilson's disease.

Causes

Hypouricemia can be caused by a variety of factors, including:

• Genetic disorders: Certain genetic conditions can lead to hypouricemia. These include Lesch-Nyhan syndrome and Wilson's disease.
• Medications: Some medications, such as allopurinol and probenecid, can lower uric acid levels.
• Diet: A diet low in purines, which are found in certain foods and drinks, can lead to hypouricemia.
• Kidney disease: Conditions that affect the kidneys, such as renal tubular acidosis and Fanconi syndrome, can cause hypouricemia.

Symptoms

The symptoms of hypouricemia can vary depending on the underlying cause. They may include:

• Fatigue
• Muscle weakness
• Joint pain
• Kidney stones

Diagnosis

Hypouricemia is typically diagnosed through a blood test that measures the level of uric acid in the blood. Additional tests may be needed to determine the underlying cause of the condition.

Treatment

Treatment for hypouricemia typically involves addressing the underlying cause of the condition. This may involve changes to diet, medication, or treatment of the associated medical condition.

See also

• Hyperuricemia
• Gout
• Uric acid
• Renal tubular acidosis
• Fanconi syndrome
• Wilson's disease