Hyperprothrombinemia

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Hyperprothrombinemia (pronounced: hi-per-pro-throm-bin-e-me-a) is a medical condition characterized by an abnormally high level of prothrombin in the blood. Prothrombin, also known as factor II, is one of the clotting factors made by the liver.

Etymology

The term "Hyperprothrombinemia" is derived from the Greek words "hyper" meaning over, "pro" meaning before, "thrombos" meaning clot, and "haima" meaning blood.

Causes

Hyperprothrombinemia can be caused by a variety of factors including genetic mutations, certain medications, and liver disease. The most common cause is a mutation in the prothrombin gene, known as Factor II mutation. This mutation increases the amount of prothrombin in the blood, leading to a higher risk of blood clots.

Symptoms

The main symptom of hyperprothrombinemia is an increased risk of developing blood clots. These clots can lead to serious conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke. Other symptoms may include unexplained bruising or bleeding, and in severe cases, thrombosis or embolism.

Diagnosis

Diagnosis of hyperprothrombinemia is typically made through blood tests that measure the level of prothrombin in the blood. Genetic testing may also be performed to identify any mutations in the prothrombin gene.

Treatment

Treatment for hyperprothrombinemia typically involves anticoagulant medications to reduce the risk of blood clots. Lifestyle changes such as regular exercise, a healthy diet, and avoiding smoking can also help manage the condition.

See Also

External links

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