Galactorrhea

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Galactorrhea
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Synonyms Galactorrhoea
Pronounce N/A
Specialty N/A
Symptoms Nipple discharge, breast tenderness, amenorrhea, infertility
Complications Hyperprolactinemia, osteoporosis
Onset Any age, commonly in reproductive years
Duration Variable
Types N/A
Causes Prolactinoma, medications, hypothyroidism, chronic kidney disease
Risks Pregnancy, stress, pituitary tumors
Diagnosis Blood test for prolactin levels, MRI of the pituitary gland
Differential diagnosis Breast cancer, mastitis, duct ectasia
Prevention N/A
Treatment Dopamine agonists, surgery, radiation therapy
Medication Cabergoline, bromocriptine
Prognosis N/A
Frequency Common
Deaths Rare


Galactorrhea refers to the unexpected production of breast milk in individuals who are neither pregnant nor have recently given birth. It is not a disease in itself, but rather a symptom of an underlying condition.

Causes

Galactorrhea can be caused by a range of factors and conditions:

  • Hormonal imbalances: An overproduction of prolactin, the hormone responsible for milk production, can result in galactorrhea.
  • Medications: Some drugs, such as certain antipsychotics, high blood pressure medications, or hormonal therapies, can induce galactorrhea as a side effect.
  • Pituitary gland tumors: Noncancerous tumors of the pituitary gland, known as prolactinomas, can cause an excess production of prolactin.
  • Hypothyroidism: Underactivity of the thyroid gland can lead to an increased prolactin level.
  • Chest injuries or surgeries.
  • Herbal supplements: Supplements such as fenugreek or fennel might lead to breast milk production.

Symptoms

While the primary symptom of galactorrhea is the production of breast milk, other symptoms may accompany the condition:

  • Irregular menstrual periods or absence of periods.
  • Unintended weight gain or loss.
  • Reduced libido or impotence.
  • Visual disturbances.
  • Acne or excessive facial hair growth.

Diagnosis

A comprehensive medical history, physical examination, and certain tests can help diagnose the cause of galactorrhea:

  • Blood tests: To measure hormone levels, especially prolactin.
  • Mammography or ultrasound: To visualize breast tissue.
  • MRI: If a pituitary tumor is suspected.

Treatment

Treatment for galactorrhea largely depends on its cause:

  • Adjusting medications: If a particular drug is suspected, an alternative might be recommended.
  • Hormone therapies: For hormone imbalances.
  • Surgery or medication: To treat pituitary tumors.

Complications

While galactorrhea itself isn't necessarily harmful, the underlying cause may lead to complications if left untreated.

Prevention

Avoiding drugs and herbal supplements that can induce galactorrhea may prevent its occurrence. Regular medical check-ups can also help identify potential hormonal imbalances early on.

See Also

References

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Contributors: Prab R. Tumpati, MD