Citric Acid Cycle

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Citric Acid Cycle

The Citric Acid Cycle (pronunciation: /ˈsɪtrɪk ˈæsɪd ˈsaɪkəl/), also known as the Krebs Cycle or the Tricarboxylic Acid Cycle (TCA cycle), is a series of chemical reactions used by all aerobic organisms to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins into Adenosine Triphosphate (ATP) and carbon dioxide.

Etymology

The Citric Acid Cycle is named after the citric acid molecule that is consumed and then regenerated by the cycle. The cycle is also named the Krebs Cycle after Hans Adolf Krebs, the biochemist awarded the Nobel Prize in Physiology or Medicine in 1953 for his discovery of the cycle.

Process

The Citric Acid Cycle begins with the reaction between acetyl-CoA and the four-carbon oxaloacetate to form six-carbon citrate. The cycle ends with the regeneration of oxaloacetate. This cycle is part of the larger process of Cellular Respiration, which also includes Glycolysis and the Electron Transport Chain.

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