Azurophilic granule

Azurophilic granules (pronunciation: /ˌæzʊˈrɒfɪlɪk ˈɡrænjuːl/) are a type of granule found in certain immune cells, particularly neutrophils. They are named for their affinity for azure dyes, which is a characteristic feature of these granules.

Etymology

The term "azurophilic" is derived from the Greek words "azure," meaning blue, and "philos," meaning loving. This refers to the granules' affinity for azure dyes. The term "granule" comes from the Latin "granulum," which means small grain.

Function

Azurophilic granules are involved in the immune response. They contain various enzymes, including myeloperoxidase, lysozyme, and defensins, which help to destroy invading pathogens. When a neutrophil encounters a pathogen, it releases the contents of its azurophilic granules, a process known as degranulation. This helps to kill the pathogen and prevent infection.

Related Terms

Neutrophil: A type of white blood cell that contains azurophilic granules.
Granule: A small particle or grain, in this context referring to the small structures within cells.
Myeloperoxidase: An enzyme found in azurophilic granules that helps to kill bacteria.
Lysozyme: An enzyme that breaks down the cell walls of bacteria, found in azurophilic granules.
Defensins: Small proteins found in azurophilic granules that have antimicrobial properties.
Degranulation: The process by which a cell releases the contents of its granules.

External links

Medical encyclopedia article on Azurophilic granule
Wikipedia's article - Azurophilic granule

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Azurophilic granule