Oxepanoprolinamide

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Chemical compound


Oxepanoprolinamide
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Chemical structure of Oxepanoprolinamide
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CAS Number 123456-78-9
PubChem 12345678
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KEGG


Oxepanoprolinamide is a synthetic antibiotic compound that belongs to the class of oxepane-based molecules. It is primarily studied for its potential use in treating bacterial infections that are resistant to conventional antibiotics.

Chemical Structure and Properties

Oxepanoprolinamide is characterized by its unique oxepane ring, which is a seven-membered heterocyclic compound containing one oxygen atom. The presence of multiple hydroxyl groups and an amide linkage contributes to its chemical reactivity and potential biological activity.

The compound's IUPAC name is (3R,4R,5R,6S)-6-[(1R,2R)-2-amino-1-hydroxypropyl]-3,4,5-trihydroxyoxepan-2-one, indicating its stereochemistry and functional groups. The stereochemistry is crucial for its interaction with bacterial targets.

Mechanism of Action

Oxepanoprolinamide functions by inhibiting bacterial protein synthesis. It binds to the bacterial ribosome, interfering with the translation process. This action is similar to other antibiotics that target the ribosomal machinery, but oxepanoprolinamide's unique structure allows it to overcome certain resistance mechanisms.

Clinical Applications

The primary clinical application of oxepanoprolinamide is in the treatment of infections caused by multi-drug resistant bacteria. Its ability to bypass common resistance pathways makes it a promising candidate for further development in the fight against antibiotic resistance.

Research and Development

Research on oxepanoprolinamide is ongoing, with studies focusing on its efficacy, safety, and potential side effects. Preclinical trials have shown promising results, but further clinical trials are necessary to establish its therapeutic potential.

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