Mequitazine

Mequitazine is a first-generation H1 receptor antagonist that is used in the treatment of allergic conditions such as hay fever, urticaria, and asthma. It is marketed under various brand names including Primalan.

Pharmacology

Mequitazine works by blocking the action of histamine, a substance in the body that causes allergic symptoms. It is a competitive antagonist at the H1 receptor, which means it prevents histamine from binding to this receptor and triggering an allergic response.

Uses

Mequitazine is used to relieve symptoms of allergic conditions such as hay fever, urticaria, and asthma. These symptoms can include sneezing, runny nose, itchy eyes, and wheezing. It can also be used to treat insomnia due to its sedative effects.

Side Effects

Common side effects of mequitazine include drowsiness, dizziness, dry mouth, and blurred vision. Less common side effects can include nausea, headache, and palpitations. In rare cases, it can cause seizures or hallucinations.

Contraindications

Mequitazine should not be used in people with a known hypersensitivity to the drug or any of its components. It should also be used with caution in people with glaucoma, prostate problems, or urinary retention.

Interactions

Mequitazine can interact with other medications, including other antihistamines, sedatives, tranquilizers, and alcohol. These interactions can increase the sedative effects of mequitazine.

Dosage

The dosage of mequitazine will depend on the individual and the condition being treated. It is usually taken once or twice a day.

See Also

• Antihistamine
• H1 antagonist
• Allergy

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