Ciclotizolam

Ciclotizolam structure

Ciclotizolam<ref>DE Patent 2445430</ref> (WE-973) is a drug which is a thienobenzodiazepine derivative. It is a partial agonist for the benzodiazepine site of the GABA_A receptor, with similar binding affinity to related compounds like brotizolam, but a low efficacy.<ref name="pmid2986988">Weber KH, Kuhn FJ, Böke-Kuhn K, Lehr E, Danneberg PB, Hommer D, Paul SM, Skolnick P,

 Pharmacological and neurochemical properties of 1,4-diazepines with two annelated heterocycles ('hetrazepines'), 
 European Journal of Pharmacology, 
 
 Vol. 109(Issue: 1),
 pp. 19–31,
 DOI: 10.1016/0014-2999(85)90535-7,
 PMID: 2986988,</ref><ref name="pmid2569655">Ikeda M, Weber KH, Bechtel WD, Malatynska E, Yamamura HI, 
 Relative efficacies of 1,4-diazepines on GABA-stimulated chloride influx in rat brain vesicles, 
 Life Sciences, 
 1989,
 Vol. 45(Issue: 4),
 pp. 349–58,
 DOI: 10.1016/0024-3205(89)90145-8,
 PMID: 2569655,</ref>

See also

• Benzodiazepine

References

<references/>

Benzodiazipines

• Alprazolam
• Chlordiazepoxide
• Diazepam (Oral)
• Estazolam
• Flurazepam
• Lorazepam
• Midazolam
• Oxazepam
• Quazepam
• Temazepam
• Triazolam

Anticonvulsants Drugs

• Clobazam
• Clonazepam
• Clorazepate
• Diazepam (Intravenous)

Anticonvulsants, and Benzodiazepines]

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