Waldmann disease: Difference between revisions
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{{Infobox medical condition | |||
| name = Waldmann disease | |||
| image = [[File:Primary_intestinal_lymphangiectasia_(Waldmann's_disease)_-_legs.jpg|250px]] | |||
| caption = Legs affected by Waldmann disease | |||
| synonyms = Primary intestinal lymphangiectasia | |||
| pronounce = | |||
| specialty = [[Gastroenterology]], [[Immunology]] | |||
| symptoms = [[Edema]], [[diarrhea]], [[abdominal pain]], [[protein-losing enteropathy]] | |||
| complications = [[Malnutrition]], [[immunodeficiency]] | |||
| onset = Childhood or early adulthood | |||
| duration = Chronic | |||
| types = | |||
| causes = [[Congenital]] malformation of intestinal lymphatics | |||
| risks = | |||
| diagnosis = [[Endoscopy]], [[biopsy]], [[imaging studies]] | |||
| differential = [[Crohn's disease]], [[celiac disease]], [[Whipple's disease]] | |||
| prevention = | |||
| treatment = [[Dietary management]], [[medium-chain triglycerides]], [[albumin]] infusions | |||
| medication = | |||
| prognosis = Variable, depends on severity and management | |||
| frequency = Rare | |||
| deaths = | |||
}} | |||
'''Vasoplegic syndrome''' is a medical condition characterized by low systemic vascular resistance, leading to hypotension. It is often associated with high cardiac output and can occur in various clinical scenarios, including after cardiac surgery. | '''Vasoplegic syndrome''' is a medical condition characterized by low systemic vascular resistance, leading to hypotension. It is often associated with high cardiac output and can occur in various clinical scenarios, including after cardiac surgery. | ||
== Causes == | == Causes == | ||
The exact cause of vasoplegic syndrome is not fully understood. However, it is believed to be related to an imbalance in the body's regulation of blood vessel dilation and constriction. This can be triggered by various factors, including: | The exact cause of vasoplegic syndrome is not fully understood. However, it is believed to be related to an imbalance in the body's regulation of blood vessel dilation and constriction. This can be triggered by various factors, including: | ||
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* [[Cancer]] | * [[Cancer]] | ||
* Use of certain medications, such as [[vasodilators]] | * Use of certain medications, such as [[vasodilators]] | ||
== Symptoms == | == Symptoms == | ||
The primary symptom of vasoplegic syndrome is [[hypotension]] (low blood pressure), despite normal or high cardiac output. Other symptoms can vary depending on the underlying cause and may include: | The primary symptom of vasoplegic syndrome is [[hypotension]] (low blood pressure), despite normal or high cardiac output. Other symptoms can vary depending on the underlying cause and may include: | ||
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* Warm and flushed skin | * Warm and flushed skin | ||
* Low urine output | * Low urine output | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of vasoplegic syndrome is typically based on the clinical presentation and the exclusion of other causes of hypotension. Diagnostic tests may include: | Diagnosis of vasoplegic syndrome is typically based on the clinical presentation and the exclusion of other causes of hypotension. Diagnostic tests may include: | ||
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* [[Echocardiogram]] | * [[Echocardiogram]] | ||
* [[Cardiac catheterization]] | * [[Cardiac catheterization]] | ||
== Treatment == | == Treatment == | ||
Treatment of vasoplegic syndrome aims to correct the hypotension and improve organ perfusion. This may involve: | Treatment of vasoplegic syndrome aims to correct the hypotension and improve organ perfusion. This may involve: | ||
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* [[Inotropic agents]] | * [[Inotropic agents]] | ||
* Treatment of the underlying cause | * Treatment of the underlying cause | ||
== Prognosis == | == Prognosis == | ||
The prognosis of vasoplegic syndrome can vary greatly depending on the underlying cause and the patient's overall health. In some cases, it can be a life-threatening condition requiring intensive care. | The prognosis of vasoplegic syndrome can vary greatly depending on the underlying cause and the patient's overall health. In some cases, it can be a life-threatening condition requiring intensive care. | ||
== See also == | == See also == | ||
* [[Cardiac output]] | * [[Cardiac output]] | ||
* [[Vascular resistance]] | * [[Vascular resistance]] | ||
* [[Hypotension]] | * [[Hypotension]] | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
[[Category:Cardiology]] | [[Category:Cardiology]] | ||
[[Category:Intensive care medicine]] | [[Category:Intensive care medicine]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 06:41, 6 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Waldmann disease | |
|---|---|
| Synonyms | Primary intestinal lymphangiectasia |
| Pronounce | |
| Specialty | Gastroenterology, Immunology |
| Symptoms | Edema, diarrhea, abdominal pain, protein-losing enteropathy |
| Complications | Malnutrition, immunodeficiency |
| Onset | Childhood or early adulthood |
| Duration | Chronic |
| Types | |
| Causes | Congenital malformation of intestinal lymphatics |
| Risks | |
| Diagnosis | Endoscopy, biopsy, imaging studies |
| Differential diagnosis | Crohn's disease, celiac disease, Whipple's disease |
| Prevention | |
| Treatment | Dietary management, medium-chain triglycerides, albumin infusions |
| Medication | |
| Prognosis | Variable, depends on severity and management |
| Frequency | Rare |
| Deaths | |
Vasoplegic syndrome is a medical condition characterized by low systemic vascular resistance, leading to hypotension. It is often associated with high cardiac output and can occur in various clinical scenarios, including after cardiac surgery.
Causes[edit]
The exact cause of vasoplegic syndrome is not fully understood. However, it is believed to be related to an imbalance in the body's regulation of blood vessel dilation and constriction. This can be triggered by various factors, including:
- Cardiac surgery
- Sepsis
- Cancer
- Use of certain medications, such as vasodilators
Symptoms[edit]
The primary symptom of vasoplegic syndrome is hypotension (low blood pressure), despite normal or high cardiac output. Other symptoms can vary depending on the underlying cause and may include:
- Tachycardia (fast heart rate)
- Warm and flushed skin
- Low urine output
Diagnosis[edit]
Diagnosis of vasoplegic syndrome is typically based on the clinical presentation and the exclusion of other causes of hypotension. Diagnostic tests may include:
Treatment[edit]
Treatment of vasoplegic syndrome aims to correct the hypotension and improve organ perfusion. This may involve:
- Intravenous fluids
- Vasopressors
- Inotropic agents
- Treatment of the underlying cause
Prognosis[edit]
The prognosis of vasoplegic syndrome can vary greatly depending on the underlying cause and the patient's overall health. In some cases, it can be a life-threatening condition requiring intensive care.


